ENSGALG00000034007


Gallus gallus

Features
Gene ID: ENSGALG00000034007
  
Biological name :ITGA6
  
Synonyms : integrin alpha-6 precursor / ITGA6
  
Possible biological names infered from orthology : Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain / integrin subunit alpha 6 / P23229 / Q61739
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 17799837
Gene end: 17838429
  
Corresponding Affymetrix probe sets: Gga.2967.1.S1_at (Chicken Array)   Gga.2967.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053194
Ensembl peptide - ENSGALP00000064434
Ensembl peptide - ENSGALP00000056234
Ensembl peptide - ENSGALP00000053453
NCBI entrez gene - 396226     See in Manteia.
RefSeq - XM_015289643
RefSeq - NM_205289
RefSeq - XM_015289641
RefSeq - XM_015289642
RefSeq Peptide - NP_990620
swissprot - A0A1L1RZY6
swissprot - A0A1D5PTI6
swissprot - A0A1D5PKU0
swissprot - A0A1D5PK42
Ensembl - ENSGALG00000034007
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU469503.1ENSDARG00000099348Danio rerio
 itga6aENSDARG00000042282Danio rerio
 itga6bENSDARG00000069946Danio rerio
 itga6lENSDARG00000056018Danio rerio
 ITGA6ENSG00000091409Homo sapiens
 Itga6ENSMUSG00000027111Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGA3 / integrin alpha-3 precursor / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSGALG0000003270234
ITGA8 / integrin alpha-8 precursor / A2ARA8* / P53708* / integrin subunit alpha 8* / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain*ENSGALG0000000874726
ITGA9 / integrin alpha-9 precursor / B8JK39* / Q13797* / Integrin alpha-9 * / integrin subunit alpha 9*ENSGALG0000002937825
ITGAV / integrin alpha-V precursor / P06756* / P43406* / integrin subunit alpha V* / Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain*ENSGALG0000000265525
ITGA4 / integrin subunit alpha 4 / P13612*ENSGALG0000004157724
ITGA2 / integrin subunit alpha 2 / P17301* / Q62469* / Integrin alpha-2 *ENSGALG0000001490321
ITGA11 / integrin subunit alpha 11 / Q9UKX5*ENSGALG0000000800719
ITGA1 / integrin alpha-1 precursor / Q3V3R4* / P56199* / Integrin alpha-1 * / integrin subunit alpha 1*ENSGALG0000001489119
ITGAD* / ITGAM* / ITGAX* / P11215* / P20702* / Q13349* / Q3V0T4* / Q9QXH4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integrin subunit alpha...ENSGALG0000004129817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0010668 ectodermal cell differentiation IEA
 biological_processGO:0022409 positive regulation of cell-cell adhesion IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031589 cell-substrate adhesion IEA
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0033627 cell adhesion mediated by integrin IEA
 biological_processGO:0035878 nail development IEA
 biological_processGO:0042327 positive regulation of phosphorylation IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046847 filopodium assembly IEA
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:0050873 brown fat cell differentiation IEA
 biological_processGO:0050900 leukocyte migration IEA
 biological_processGO:0072001 renal system development IEA
 biological_processGO:0097186 amelogenesis IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009925 basal plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0030056 hemidesmosome IEA
 cellular_componentGO:0045178 basal part of cell IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0031994 insulin-like growth factor I binding IEA
 molecular_functionGO:0038132 neuregulin binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Basigin interactions
Integrin cell surface interactions
Laminin interactions
Syndecan interactions
Type I hemidesmosome assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007145 ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *  / complex
 ENSGALG00000004620 LAMC1 / laminin subunit gamma 1 / P11047*  / complex / reaction
 ENSGALG00000001328 BSG / P17790 / Basigin / P18572* / P35613* / basigin (Ok blood group)*  / reaction / complex
 ENSGALG00000006856 CD151 / CD151 molecule (Raph blood group) / O35566* / P48509* / CD151 antigen *  / complex / reaction






 

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