ENSDARG00000042282


Danio rerio

Features
Gene ID: ENSDARG00000042282
  
Biological name :itga6a
  
Synonyms : integrin, alpha 6a / itga6a
  
Possible biological names infered from orthology : Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain / integrin subunit alpha 6 / ITGA6 / P23229 / Q61739
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 3429662
Gene end: 3486488
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000076590
Ensembl peptide - ENSDARP00000098022
NCBI entrez gene - 503893     See in Manteia.
RefSeq - XM_005167409
RefSeq - XM_005167411
swissprot - A8WHQ8
swissprot - A8WHQ7
ZFIN ID - ZDB-GENE-050309-23
Ensembl - ENSDARG00000042282
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGA6ENSGALG00000034007Gallus gallus
 ITGA6ENSG00000091409Homo sapiens
 Itga6ENSMUSG00000027111Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itga6b / integrin, alpha 6b / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000006994661
itga6l / integrin, alpha 6, like / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000005601846
CU469503.1 / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000009934836
itga3a / integrin, alpha 3a / ITGA3* / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSDARG0000003791732
itga3b / integrin, alpha 3b / ITGA3* / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSDARG0000001282432
itgav / integrin, alpha V / P06756* / integrin subunit alpha V*ENSDARG0000000631426
itga5 / integrin, alpha 5 (fibronectin receptor, alpha polypeptide) / P08648* / P11688* / integrin subunit alpha 5* / Integrin alpha-5 Integrin alpha-5 heavy chain Integrin alpha-5 light chain*ENSDARG0000000635324
itga8 / integrin, alpha 8 / P53708* / A2ARA8* / integrin subunit alpha 8* / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain*ENSDARG0000007871724
itga4 / integrin alpha 4 / P13612* / integrin subunit alpha 4*ENSDARG0000010305623
itga9 / integrin, alpha 9 / Q13797* / integrin subunit alpha 9*ENSDARG0000003243522
itga2b / integrin, alpha 2b / P08514* / Q9QUM0* / integrin subunit alpha 2b*ENSDARG0000001868722
itga2.2 / integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2 / ITGA2* / P17301* / Q62469* / Integrin alpha-2 * / integrin subunit alpha 2*ENSDARG0000006297421
itga1 / integrin, alpha 1 / P56199* / Q3V3R4* / integrin subunit alpha 1*ENSDARG0000007431621
itga10 / integrin, alpha 10 / O75578* / integrin subunit alpha 10*ENSDARG0000000250721
itga11a / integrin, alpha 11a / ITGA11* / Q9UKX5* / integrin subunit alpha 11*ENSDARG0000003608621
itga11b / integrin, alpha 11b / ITGA11* / Q9UKX5* / integrin subunit alpha 11*ENSDARG0000000795020
si:dkey-32n7.4 / ITGAD* / ITGAM* / ITGAX* / Q13349* / P11215* / P20702* / Q9QXH4* / Q3V0T4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integ...ENSDARG0000000295617
zmp:0000001082 / ITGAL* / P20701* / P24063* / Integrin alpha-L * / integrin subunit alpha L*ENSDARG0000009889916
itgae.2 / integrin, alpha E, tandem duplicate 2 / ITGAE* / P38570* / Q60677* / integrin subunit alpha E* / integrin alpha E, epithelial-associated*ENSDARG0000005778715
itgam / integrin, alpha M (complement component 3 receptor 3 subunit) / ITGAD* / ITGAX* / P11215* / P20702* / Q13349* / Q3V0T4* / Q9QXH4* / integrin alpha M* / Integrin alpha-X * / Integrin...ENSDARG0000009658712


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0007519 skeletal muscle tissue development IMP
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Assembly of collagen fibrils and other multimeric structures
Basigin interactions
Integrin cell surface interactions
Laminin interactions
Type I hemidesmosome assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000610 vertical myoseptum vertical myoseptum U-shaped , abnormal
vertical myoseptum malformed , abnormal
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 ZFA:0001056 myotome myotome muscle tendon junction malformed , abnormal
myotome muscle tendon junction U-shaped , abnormal
myotome muscle cell degenerate , abnormal
myotome muscle cell increased length , abnormal
myotome decreased width , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001115 trunk trunk decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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