ENSDARG00000103056


Danio rerio

Features
Gene ID: ENSDARG00000103056
  
Biological name :itga4
  
Synonyms : integrin alpha 4 / itga4
  
Possible biological names infered from orthology : integrin subunit alpha 4 / P13612
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 44034790
Gene end: 44088067
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131563
Ensembl peptide - ENSDARP00000141779
Ensembl peptide - ENSDARP00000144215
NCBI entrez gene - 100331333     See in Manteia.
swissprot - A0A0R4ICS1
swissprot - A0A0R4IWQ3
ZFIN ID - ZDB-GENE-110411-108
Ensembl - ENSDARG00000103056
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGA4ENSGALG00000041577Gallus gallus
 ITGA4ENSG00000115232Homo sapiens
 Itga4ENSMUSG00000027009Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itga9 / integrin, alpha 9 / Q13797* / integrin subunit alpha 9*ENSDARG0000003243540
itga8 / integrin, alpha 8 / P53708* / A2ARA8* / integrin subunit alpha 8* / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain*ENSDARG0000007871725
itgav / integrin, alpha V / P06756* / integrin subunit alpha V*ENSDARG0000000631425
itga6a / integrin, alpha 6a / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000004228224
itga6b / integrin, alpha 6b / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000006994623
itga3b / integrin, alpha 3b / ITGA3* / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSDARG0000001282423
itga3a / integrin, alpha 3a / ITGA3* / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSDARG0000003791723
itga6l / integrin, alpha 6, like / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000005601823
itga5 / integrin, alpha 5 (fibronectin receptor, alpha polypeptide) / P08648* / P11688* / integrin subunit alpha 5* / Integrin alpha-5 Integrin alpha-5 heavy chain Integrin alpha-5 light chain*ENSDARG0000000635323
itga2b / integrin, alpha 2b / P08514* / Q9QUM0* / integrin subunit alpha 2b*ENSDARG0000001868722
itga2.2 / integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2 / ITGA2* / P17301* / Q62469* / Integrin alpha-2 * / integrin subunit alpha 2*ENSDARG0000006297422
itga11a / integrin, alpha 11a / ITGA11* / Q9UKX5* / integrin subunit alpha 11*ENSDARG0000003608621
itga11b / integrin, alpha 11b / ITGA11* / Q9UKX5* / integrin subunit alpha 11*ENSDARG0000000795021
itga10 / integrin, alpha 10 / O75578* / integrin subunit alpha 10*ENSDARG0000000250721
itga1 / integrin, alpha 1 / P56199* / Q3V3R4* / integrin subunit alpha 1*ENSDARG0000007431620
si:dkey-32n7.4 / ITGAD* / ITGAM* / ITGAX* / Q13349* / P11215* / P20702* / Q9QXH4* / Q3V0T4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integ...ENSDARG0000000295619
zmp:0000001082 / ITGAL* / P20701* / P24063* / Integrin alpha-L * / integrin subunit alpha L*ENSDARG0000009889919
itgae.2 / integrin, alpha E, tandem duplicate 2 / ITGAE* / P38570* / Q60677* / integrin subunit alpha E* / integrin alpha E, epithelial-associated*ENSDARG0000005778716
itgam / integrin, alpha M (complement component 3 receptor 3 subunit) / ITGAD* / ITGAX* / P11215* / P20702* / Q13349* / Q3V0T4* / Q9QXH4* / integrin alpha M* / Integrin alpha-X * / Integrin...ENSDARG0000009658714
CU469503.1 / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000009934810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010785 thbs1b / thrombospondin 1b / THBS1* / P07996* / thrombospondin 1*  / reaction / complex
 ENSDARG00000062479 vcam1b / vascular cell adhesion molecule 1b / VCAM1* / P19320* / P29533* / vascular cell adhesion molecule 1*  / complex / reaction
 ENSDARG00000114589 jam3a / junctional adhesion molecule 3a / JAM3* / Q9BX67* / Q9D8B7* / junctional adhesion molecule 3* / Junctional adhesion molecule C *  / reaction / complex
 ENSDARG00000071863 itgb1a / integrin, beta 1a / ITGB1* / P05556* / P09055* / Integrin beta-1 * / integrin subunit beta 1*  / complex
 ENSDARG00000079071 jam2b / junctional adhesion molecule 2b / JAM2* / P57087* / Q9JI59* / junctional adhesion molecule 2* / Junctional adhesion molecule B *  / reaction / complex






 

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