ENSGALG00000044053


Gallus gallus

Features
Gene ID: ENSGALG00000044053
  
Biological name :NLRX1
  
Synonyms : NLR family member X1 / NLRX1
  
Possible biological names infered from orthology : Q3TL44 / Q86UT6
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 4264395
Gene end: 4269225
  
Corresponding Affymetrix probe sets: GgaAffx.20475.1.S1_at (Chicken Array)   GgaAffx.20475.1.S1_s_at (Chicken Array)   GgaAffx.20580.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010953
NCBI entrez gene - 419755     See in Manteia.
RefSeq - XM_003642592
RefSeq - XM_015298203
RefSeq - XM_004948038
RefSeq - XM_015298202
swissprot - E1C894
Ensembl - ENSGALG00000044053
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nlrx1ENSDARG00000073724Danio rerio
 NLRX1ENSG00000160703Homo sapiens
 Nlrx1ENSMUSG00000032109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLRC3 / NLR family CARD domain containing 3 / Q5DU56* / Q7RTR2* / Protein NLRC3 *ENSGALG0000003327817
NLRC5 / Gallus gallus NLR family CARD domain containing 5 (NLRC5), mRNA. / C3VPR6* / Q86WI3* / Protein NLRC5 * / NLR family CARD domain containing 5*ENSGALG0000000125615
CIITA / class II major histocompatibility complex transactivator / P33076* / P79621* / MHC class II transactivator *ENSGALG0000000717113
NOD1 / Gallus gallus nucleotide binding oligomerization domain containing 1 (NOD1), mRNA. / Q8BHB0* / Q9Y239* / nucleotide binding oligomerization domain containing 1* / Nucleotide-binding ...ENSGALG0000003680713


Protein motifs (from Interpro)
Interpro ID Name
 IPR007111  NACHT nucleoside triphosphatase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032688 negative regulation of interferon-beta production IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0039536 negative regulation of RIG-I signaling pathway IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045824 negative regulation of innate immune response IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
RLR (RIG-like receptor) mediated induction of IFN alpha/beta
Negative Regulation of MDA5 signaling
Negative regulators of DDX58/IFIH1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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