ENSGALG00000036807


Gallus gallus

Features
Gene ID: ENSGALG00000036807
  
Biological name :NOD1
  
Synonyms : Gallus gallus nucleotide binding oligomerization domain containing 1 (NOD1), mRNA. / NOD1
  
Possible biological names infered from orthology : nucleotide binding oligomerization domain containing 1 / Nucleotide-binding oligomerization domain-containing protein 1 / Q8BHB0 / Q9Y239
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 41382382
Gene end: 41402668
  
Corresponding Affymetrix probe sets: Gga.7950.1.S1_at (Chicken Array)   GgaAffx.7309.1.S1_at (Chicken Array)   GgaAffx.7309.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056185
NCBI entrez gene - 420677     See in Manteia.
RefSeq - XM_418777
RefSeq - NM_001318438
RefSeq - XM_015281771
RefSeq - XM_015281772
RefSeq Peptide - NP_001305367
swissprot - A0A1D5PTE0
Ensembl - ENSGALG00000036807
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nod1ENSDARG00000036308Danio rerio
 NOD1ENSG00000106100Homo sapiens
 Nod1ENSMUSG00000038058Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLRC3 / NLR family CARD domain containing 3 / Q5DU56* / Q7RTR2* / Protein NLRC3 *ENSGALG0000003327822
NLRC5 / Gallus gallus NLR family CARD domain containing 5 (NLRC5), mRNA. / C3VPR6* / Q86WI3* / Protein NLRC5 * / NLR family CARD domain containing 5*ENSGALG0000000125619
CIITA / class II major histocompatibility complex transactivator / P33076* / P79621* / MHC class II transactivator *ENSGALG0000000717116
NLRX1 / NLR family member X1 / Q3TL44* / Q86UT6*ENSGALG0000004405313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR001611  Leucine-rich repeat
 IPR007111  NACHT nucleoside triphosphatase
 IPR011029  Death-like domain superfamily
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002606 positive regulation of dendritic cell antigen processing and presentation IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0016045 detection of bacterium IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IEA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042228 interleukin-8 biosynthetic process IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0046330 positive regulation of JNK cascade IEA
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071225 cellular response to muramyl dipeptide IEA
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IEA
 biological_processGO:1904417 positive regulation of xenophagy IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0050700 CARD domain binding IEA


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016284 TAB3 / TGF-beta activated kinase 1 and MAP3K7 binding protein 3 / Q571K4* / Q8N5C8* / TGF-beta activated kinase 1/MAP3K7 binding protein 3*  / complex / reaction
 ENSGALG00000012356 TAB2 / TGF-beta activated kinase 1/MAP3K7 binding protein 2 / Q99K90* / Q9NYJ8* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 *  / reaction / complex
 ENSGALG00000015596 MAP3K7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*  / reaction / complex
 ENSGALG00000012150 TAB1 / TGF-beta activated kinase 1 (MAP3K7) binding protein 1 / Q15750* / Q8CF89* / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 *  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex
 ENSGALG00000043535 RIPK2 / receptor-interacting serine/threonine-protein kinase 2 / O43353* / P58801* / receptor interacting serine/threonine kinase 2* / receptor (TNFRSF)-interacting serine-threonine kinase 2*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex
 ENSGALG00000036807 NOD1 / Gallus gallus nucleotide binding oligomerization domain containing 1 (NOD1), mRNA. / Q8BHB0* / Q9Y239* / nucleotide binding oligomerization domain containing 1* / Nucleotide-binding ...  / complex / reaction






 

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