ENSMUSG00000001804


Mus musculus

Features
Gene ID: ENSMUSG00000001804
  
Biological name :Dsg4
  
Synonyms : Desmoglein-4 / Dsg4 / Q7TMD7
  
Possible biological names infered from orthology : Q86SJ6
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: A2
Gene start: 20436175
Gene end: 20471821
  
Corresponding Affymetrix probe sets: 10454134 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000019426
NCBI entrez gene - 16769     See in Manteia.
MGI - MGI:2661061
RefSeq - NM_181564
RefSeq Peptide - NP_853543
swissprot - Q7TMD7
Ensembl - ENSMUSG00000001804
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-74h11.1ENSDARG00000062750Danio rerio
 ENSGALG00000017398Gallus gallus
 DSG4ENSG00000175065Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dsg1a / Q61495 / Desmoglein-1-alpha / DSG1* / Q02413* / desmoglein 1*ENSMUSG0000006944145
Dsg1b / Q7TSF1 / Desmoglein-1-beta / DSG1* / Q02413* / desmoglein 1*ENSMUSG0000006192845
Dsg3 / desmoglein 3 / P32926*ENSMUSG0000005663245
Dsg1c / Q7TSF0 / Desmoglein-1-gamma / DSG1* / Q02413* / desmoglein 1*ENSMUSG0000003477441
Dsg2 / O55111 / Desmoglein-2 / Q14126*ENSMUSG0000004439336


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR009122  Desmosomal cadherin
 IPR009123  Desmoglein
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001942 hair follicle development IDA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0030216 keratinocyte differentiation IMP
 biological_processGO:0030509 BMP signaling pathway IDA
 biological_processGO:0098609 cell-cell adhesion IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030057 desmosome IMP
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000359 abnormal mast cell morphology "anomalous structure of these granulated cells found in most tissues, but most abundantly in skin and g.i. tract" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

 MP:0000377 abnormal hair follicle "malformed invagination of the epidermis from which the hair shaft develops" [J:65031]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

 MP:0000381 enlarged hair follicles "increased size of the epidermal invaginations from which the hair shaft develops" [J:30249]
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Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0000383 abnormal hair follicle orientation "misaligned hair follicles; hair follicles that do not orient in a typical pattern" [J:47620]
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Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

 MP:0000384 distorted hair follicle pattern "twisted or contorted configuration of the arrangement of hair follicles in the skin" [J:56777]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0000416 sparse fur "fur that is significantly less dense" [J:46854]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

Allelic Composition: Dsg4tbird/Dsg4tbird
Genetic Background: either: C57BL/6JAnu-Dsg4tbird/Apb or B10.B6JAnu-Dsg4tbird/Apb or (involves: C57BL/6JAnu * C57BL/10 * CBA)

 MP:0000417 short hair "reduced average length of the hairs" [J:64948]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0000580 deformed nails "atypical shape or size of the nails" [J:45400]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0000583 long toenails "increased length of the toenails" [J:65045]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0000647 abnormal sebaceous gland morphology "malformation of the holocrine glands of the dermis that secrete sebum into the hair follicles" [MGI:tc]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001190 reddish skin "skin has a more intense ruddy appearance than normal, often due to capillary congestion" [J:65038]
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Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0001191 abnormal skin condition "anomalous state of the skin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001192 scaly skin "skin covered with shedding scales or flakes" [J:65146]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0001194 dermatitis "inflammation of the skin" [J:65146]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0001200 thick skin "greater depth of skin " [J:47225]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0001211 wrinkled skin "irregular folds and/or indentations on the skin" [J:19212]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

 MP:0001222 epidermal hyperplasia "increase in size of the epidermis due to increase in epidermal cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0001242 hyperkeratosis "increased depth of the corneal layer of the epidermis; thickening of the horny layer of the epidermis" [J:1133]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0001245 thick dermal layer "increased depth of the dermis" [J:65033]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001246 mixed cellular infiltration to dermis "gradual accumulation of mixed cell types in the dermis that are not normally found there" [J:65416]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0001279 wavy vibrissae "whiskers having undulations or a sinusoidal shape" [J:65044]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0001282 short vibrissae "decreased length of the vibrissae" [J:30249]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0001284 absent vibrissae "missing whiskers" [J:18378]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

Allelic Composition: Dsg4tbird/Dsg4tbird
Genetic Background: either: C57BL/6JAnu-Dsg4tbird/Apb or B10.B6JAnu-Dsg4tbird/Apb or (involves: C57BL/6JAnu * C57BL/10 * CBA)

 MP:0001661 extended life span "persistence of life for a longer period than is the norm for an organism" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

 MP:0001786 skin edema "accumulation of an excessive amount of fluid in the skin" [J:65039]
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Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0001874 acanthosis "diffuse hyperplasia of the spinous layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0002073 abnormal hair growth "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0002074 abnormal hair texture "irregular or unusual appearance of the structure of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0002095 abnormal skin pigmentation "variation of skin color or complexion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0002435 abnormal effector T cell morphology/development "anomalous structure, formation, or numbers of the set of T lymphocytes that are able to respond immediately upon contact with cells bearing the appropriate peptide:MHC complex for the cell" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dsg4hage/Dsg4hage,Faslpr/Faslpr,X/Yaa
Genetic Background: EOD-Dsg4hage

 MP:0002497 increased IgE "greater than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0003089 reduced skin tensile strength "reduction in the normal maximum tension the skin can withstand without tearing" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, J:48068]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0003413 hair follicle degeneration "a retrogressive impairment of function or destruction of the hair follicle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:94517]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0003427 parakeratosis "abnormal retention of the nuclei of the keratinocytes in the stratum corneum of the epidermis" [smb:Susan M Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0003809 abnormal hair shaft morphology "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0003811 abnormal hair cortex "anomalies in the spindle shaped cells of the hair shaft that contains keratin fibrils and matrix" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0003848 brittle hair "hair is susceptible to breakage " [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0003849 greasy coat "fur is oily in appearance or texture" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Dsg4tbird/Dsg4tbird
Genetic Background: either: C57BL/6JAnu-Dsg4tbird/Apb or B10.B6JAnu-Dsg4tbird/Apb or (involves: C57BL/6JAnu * C57BL/10 * CBA)

 MP:0006365 absent guard hair "absence of the long, straight truncal hairs that contain two air cells in the medulla" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0008463 abnormal peripheral lymph node morphology "any structural anomaly of the lymph nodes located outside the thoracic and abdominal cavities, such as the submandibular, prescapular, axillary, inguinal and popliteal lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0008853 decreased abdominal adipose tissue amount "reduction in amount of adipose tissue associated with internal organs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0008858 abnormal hair cycle anagen phase "anomaly in the growth phase of the hair cycle" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0008859 abnormal hair cycle catagen phase "anomaly in the phase of the hair growth cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored hair is produced" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0010179 rough coat "coat does not have the usual smooth appearance" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0010685 abnormal hair follicle inner root sheath morphology "any structural anomaly of the multilayered tube composed of terminally differentiated hair follicle keratinocytes that is surrounded by the outer root sheath; the layers of the inner root sheath include the companion layer, Henle s layer, Huxley s layer and the inner root sheath cuticle" [PMID:19211055]
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Allelic Composition: Dsg4arm/Dsg4arm
Genetic Background: involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd

 MP:0010688 hair follicle outer rooth sheath hyperplasia "overdevelopment or increased size, usually due to a increased number of cells, outermost layer of the hair follicle that merges proximally with the basal layer of the interfollicular epidermis and distally with the hair bulb" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Dsg4lah/Dsg4lah
Genetic Background: LAH/Pas

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Otx1tm4(cre)Asim/Otx1+,Otx2tm6Asim/Otx2tm6.1Asim
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0013115 focal hair loss in abdominal region "focal absence of hair on the abdomen, in those areas where hair is normally expected, resulting in visible patches of skin and uneven spots of hair growth on the body" [MGI:Ahmad_Retha, MGI:csmith]
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Allelic Composition: Dock2m7Btlr/Dock2+
Genetic Background: C57BL/6J-Dock2m7Btlr

 MP:0013116 focal hair loss in head/neck region "focal absence of hair in the head and/or neck region, in those areas where hair is normally expected, resulting in visible patches of skin and uneven spots of hair growth on the body" [MGI:Ahmad_Retha, MGI:csmith]
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Allelic Composition: Dock2m7Btlr/Dock2+
Genetic Background: C57BL/6J-Dock2m7Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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