ENSMUSG00000069441


Mus musculus

Features
Gene ID: ENSMUSG00000069441
  
Biological name :Dsg1a
  
Synonyms : Desmoglein-1-alpha / Dsg1a / Q61495
  
Possible biological names infered from orthology : desmoglein 1 / DSG1 / Q02413
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: A2
Gene start: 20310811
Gene end: 20343350
  
Corresponding Affymetrix probe sets: 10454113 (MoGene1.0st)   1458000_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076393
NCBI entrez gene - 13510     See in Manteia.
MGI - MGI:94930
RefSeq - NM_010079
RefSeq Peptide - NP_034209
swissprot - Q61495
Ensembl - ENSMUSG00000069441
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-74h11.1ENSDARG00000062750Danio rerio
 ENSGALG00000017398Gallus gallus
 DSG1ENSG00000134760Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dsg1b / Q7TSF1 / Desmoglein-1-beta / DSG1* / Q02413* / desmoglein 1*ENSMUSG0000006192895
Dsg1c / Q7TSF0 / Desmoglein-1-gamma / DSG1* / Q02413* / desmoglein 1*ENSMUSG0000003477479
Dsg4 / Q7TMD7 / Desmoglein-4 / Q86SJ6*ENSMUSG0000000180444
Dsg3 / desmoglein 3 / P32926*ENSMUSG0000005663239
Dsg2 / O55111 / Desmoglein-2 / Q14126*ENSMUSG0000004439335


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR009122  Desmosomal cadherin
 IPR009123  Desmoglein
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005911 cell-cell junction ISO
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030057 desmosome TAS
 cellular_componentGO:0031012 extracellular matrix ISO
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045295 gamma-catenin binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cell adhesion proteins
Neutrophil degranulation
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031628 Casp3 / P70677 / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12 / P42574* / caspase 3*  / reaction






 

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