Manteia

ENSMUSG00000003573

Mus musculus

Features

Gene ID:	ENSMUSG00000003573

Biological name :	Homer3

Synonyms :	Homer3 / Homer protein homolog 3 / Q99JP6

Possible biological names infered from orthology :	homer scaffolding protein 3 / Q9NSC5

Species:	Mus musculus

Chr. number:	8
Strand:	1
Band:	B3.3
Gene start:	70282827
Gene end:	70294361

Corresponding Affymetrix probe sets:	10572345 (MoGene1.0st) 1424859_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000105751 Ensembl peptide - ENSMUSP00000003669 Ensembl peptide - ENSMUSP00000084735 Ensembl peptide - ENSMUSP00000117033 Ensembl peptide - ENSMUSP00000137560 NCBI entrez gene - 26558 See in Manteia. MGI - MGI:1347359 RefSeq - XM_006509681 RefSeq - NM_001146153 RefSeq - NM_011984 RefSeq - XM_006509679 RefSeq - XM_006509680 RefSeq Peptide - NP_001139625 RefSeq Peptide - NP_036114 swissprot - Q501M9 swissprot - Q99JP6 swissprot - J3QQ00 Ensembl - ENSMUSG00000003573

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Homer1 / Q9Z2Y3 / Homer protein homolog 1 / Q86YM7* / homer scaffolding protein 1*	ENSMUSG00000007617	49
Homer2 / Q9QWW1 / Homer protein homolog 2 / Q9NSB8* / homer scaffolding protein 2*	ENSMUSG00000025813	46

Protein motifs (from Interpro)

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007216	G-protein coupled glutamate receptor signaling pathway	TAS
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005829	cytosol	IDA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0014069	postsynaptic density	IDA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030054	cell junction	IEA
cellular_component	GO:0045178	basal part of cell	IDA
cellular_component	GO:0045202	synapse	IEA
cellular_component	GO:0045211	postsynaptic membrane	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0008022	protein C-terminus binding	IPI
molecular_function	GO:0019904	protein domain specific binding	IPI
molecular_function	GO:0035256	G-protein coupled glutamate receptor binding	IBA
molecular_function	GO:0042802	identical protein binding	IEA

Pathways (from Reactome)

Pathway description

Neurexins and neuroligins

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002736	abnormal nociception after inflammation	"changes in pain thresholds after inflammation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Gabbr1^tm2Bet/Gabbr1^tm2Bet,Hdc^{tm1.1(icre)Wwis}/Hdc⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000003573	Homer3 / Q99JP6 / Homer protein homolog 3 / Q9NSC5* / homer scaffolding protein 3*	/ complex / reaction
ENSMUSG00000007617	Homer1 / Q9Z2Y3 / Homer protein homolog 1 / Q86YM7* / homer scaffolding protein 1*	/ reaction / complex
ENSMUSG00000019828	Grm1 / P97772 / Metabotropic glutamate receptor 1 / Q13255* / glutamate metabotropic receptor 1*	/ reaction / complex
ENSMUSG00000049583	Grm5 / Q3UVX5 / glutamate receptor, metabotropic 5 / P41594* / glutamate metabotropic receptor 5*	/ reaction / complex
ENSMUSG00000025813	Homer2 / Q9QWW1 / Homer protein homolog 2 / Q9NSB8* / homer scaffolding protein 2*	/ reaction / complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr