ENSG00000051128


Homo sapiens

Features
Gene ID: ENSG00000051128
  
Biological name :HOMER3
  
Synonyms : HOMER3 / homer scaffolding protein 3 / Q9NSC5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 18929201
Gene end: 18941261
  
Corresponding Affymetrix probe sets: 204647_at (Human Genome U133 Plus 2.0 Array)   215489_x_at (Human Genome U133 Plus 2.0 Array)   222222_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472815
Ensembl peptide - ENSP00000471835
Ensembl peptide - ENSP00000472800
Ensembl peptide - ENSP00000221222
Ensembl peptide - ENSP00000376162
Ensembl peptide - ENSP00000396154
Ensembl peptide - ENSP00000439937
Ensembl peptide - ENSP00000446026
Ensembl peptide - ENSP00000469800
Ensembl peptide - ENSP00000470659
NCBI entrez gene - 9454     See in Manteia.
OMIM - 604800
RefSeq - XM_006722944
RefSeq - NM_001145721
RefSeq - NM_001145722
RefSeq - NM_001145724
RefSeq - NM_004838
RefSeq - XM_006722943
RefSeq Peptide - NP_001139194
RefSeq Peptide - NP_001139193
RefSeq Peptide - NP_001139196
RefSeq Peptide - NP_004829
swissprot - M0R2U7
swissprot - M0QZN1
swissprot - M0QYF9
swissprot - Q9NSC5
swissprot - M0R2T8
Ensembl - ENSG00000051128
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 homer3bENSDARG00000010789Danio rerio
 HOMER3ENSGALG00000003074Gallus gallus
 Homer3ENSMUSG00000003573Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOMER1 / Q86YM7 / homer scaffolding protein 1ENSG0000015241351
HOMER2 / Q9NSB8 / homer scaffolding protein 2ENSG0000010394244


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting TAS
 biological_processGO:0007216 G-protein coupled glutamate receptor signaling pathway TAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045178 basal part of cell IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0035256 G-protein coupled glutamate receptor binding IBA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000082458 DLG3 / Q92796 / discs large MAGUK scaffold protein 3  / complex / reaction
 ENSG00000103942 HOMER2 / Q9NSB8 / homer scaffolding protein 2  / reaction / complex
 ENSG00000152822 GRM1 / Q13255 / glutamate metabotropic receptor 1  / complex / reaction
 ENSG00000051128 HOMER3 / Q9NSC5 / homer scaffolding protein 3  / reaction / complex
 ENSG00000152413 HOMER1 / Q86YM7 / homer scaffolding protein 1  / complex / reaction
 ENSG00000168959 GRM5 / P41594 / glutamate metabotropic receptor 5  / complex / reaction
 ENSG00000116544 DLGAP3 / O95886 / DLG associated protein 3  / complex / reaction
 ENSG00000150672 DLG2 / Q15700 / discs large MAGUK scaffold protein 2  / complex / reaction
 ENSG00000161681 Q9Y566 / SHANK1 / SH3 and multiple ankyrin repeat domains 1  / reaction / complex
 ENSG00000132535 DLG4 / P78352 / discs large MAGUK scaffold protein 4  / reaction / complex
 ENSG00000170579 DLGAP1 / O14490 / DLG associated protein 1  / reaction / complex
 ENSG00000080845 DLGAP4 / Q9Y2H0 / DLG associated protein 4  / reaction / complex
 ENSG00000162105 Q9UPX8 / SHANK2 / SH3 and multiple ankyrin repeat domains 2  / complex / reaction
 ENSG00000198010 DLGAP2 / Q9P1A6 / DLG associated protein 2  / reaction / complex






 

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