ENSG00000116544


Homo sapiens

Features
Gene ID: ENSG00000116544
  
Biological name :DLGAP3
  
Synonyms : DLGAP3 / DLG associated protein 3 / O95886
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.3
Gene start: 34865436
Gene end: 34929585
  
Corresponding Affymetrix probe sets: 231151_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000235180
Ensembl peptide - ENSP00000362444
NCBI entrez gene - 58512     See in Manteia.
OMIM - 611413
RefSeq - XM_011541880
RefSeq - NM_001080418
RefSeq - XM_011541879
RefSeq Peptide - NP_001073887
swissprot - O95886
Ensembl - ENSG00000116544
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlgap3ENSDARG00000055459Danio rerio
 DLGAP3ENSGALG00000032980Gallus gallus
 Dlgap3ENSMUSG00000042388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DLGAP2 / Q9P1A6 / DLG associated protein 2ENSG0000019801049
DLGAP1 / O14490 / DLG associated protein 1ENSG0000017057941
DLGAP4 / Q9Y2H0 / DLG associated protein 4ENSG0000008084536
DLGAP5 / Q15398 / DLG associated protein 5ENSG0000012678712
MYL9 / P24844 / myosin light chain 9ENSG000001013352


Protein motifs (from Interpro)
Interpro ID Name
 IPR005026  SAPAP family
 IPR030526  Disks large-associated protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0023052 signaling IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IBA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103942 HOMER2 / Q9NSB8 / homer scaffolding protein 2  / reaction / complex
 ENSG00000051128 HOMER3 / Q9NSC5 / homer scaffolding protein 3  / complex / reaction
 ENSG00000136279 DBNL / Q9UJU6 / drebrin like  / complex / reaction
 ENSG00000152822 GRM1 / Q13255 / glutamate metabotropic receptor 1  / complex / reaction
 ENSG00000082458 DLG3 / Q92796 / discs large MAGUK scaffold protein 3  / reaction / complex
 ENSG00000168959 GRM5 / P41594 / glutamate metabotropic receptor 5  / complex / reaction
 ENSG00000132535 DLG4 / P78352 / discs large MAGUK scaffold protein 4  / reaction / complex
 ENSG00000152413 HOMER1 / Q86YM7 / homer scaffolding protein 1  / complex / reaction
 ENSG00000150672 DLG2 / Q15700 / discs large MAGUK scaffold protein 2  / reaction / complex
 ENSG00000161681 Q9Y566 / SHANK1 / SH3 and multiple ankyrin repeat domains 1  / reaction / complex
 ENSG00000162105 Q9UPX8 / SHANK2 / SH3 and multiple ankyrin repeat domains 2  / complex / reaction






 

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