ENSG00000152413


Homo sapiens

Features
Gene ID: ENSG00000152413
  
Biological name :HOMER1
  
Synonyms : HOMER1 / homer scaffolding protein 1 / Q86YM7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q14.1
Gene start: 79372636
Gene end: 79514217
  
Corresponding Affymetrix probe sets: 213793_s_at (Human Genome U133 Plus 2.0 Array)   226651_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000282260
Ensembl peptide - ENSP00000334382
Ensembl peptide - ENSP00000426651
Ensembl peptide - ENSP00000441587
NCBI entrez gene - 9456     See in Manteia.
OMIM - 604798
RefSeq - XM_017010059
RefSeq - NM_001277077
RefSeq - NM_001277078
RefSeq - NM_004272
RefSeq Peptide - NP_001264007
RefSeq Peptide - NP_004263
RefSeq Peptide - NP_001264006
swissprot - Q86YM6
swissprot - Q86YM7
Ensembl - ENSG00000152413
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 homer1bENSDARG00000101759Danio rerio
 HOMER1ENSGALG00000014813Gallus gallus
 Homer1ENSMUSG00000007617Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOMER3 / Q9NSC5 / homer scaffolding protein 3ENSG0000005112852
HOMER2 / Q9NSB8 / homer scaffolding protein 2ENSG0000010394252


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR011993  PH-like domain superfamily
 IPR019394  Testis-specific protein TEX28/transmembrane and coiled-coil domains protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IEA
 biological_processGO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway TAS
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0009967 positive regulation of signal transduction IC
 biological_processGO:0048148 behavioral response to cocaine IEA
 biological_processGO:0048741 skeletal muscle fiber development IEA
 biological_processGO:0048875 chemical homeostasis within a tissue IEA
 biological_processGO:0051592 response to calcium ion IDA
 biological_processGO:0051928 positive regulation of calcium ion transport IEA
 biological_processGO:0090279 regulation of calcium ion import IEA
 biological_processGO:2001256 regulation of store-operated calcium entry TAS
 biological_processGO:2001257 regulation of cation channel activity TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043034 costamere IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035256 G-protein coupled glutamate receptor binding IBA
 molecular_functionGO:0035591 signaling adaptor activity IC
 molecular_functionGO:0044325 ion channel binding IPI


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000082458 DLG3 / Q92796 / discs large MAGUK scaffold protein 3  / complex / reaction
 ENSG00000051128 HOMER3 / Q9NSC5 / homer scaffolding protein 3  / reaction / complex
 ENSG00000116544 DLGAP3 / O95886 / DLG associated protein 3  / complex / reaction
 ENSG00000152822 GRM1 / Q13255 / glutamate metabotropic receptor 1  / complex / reaction
 ENSG00000168959 GRM5 / P41594 / glutamate metabotropic receptor 5  / reaction / complex
 ENSG00000150672 DLG2 / Q15700 / discs large MAGUK scaffold protein 2  / complex / reaction
 ENSG00000161681 Q9Y566 / SHANK1 / SH3 and multiple ankyrin repeat domains 1  / complex / reaction
 ENSG00000132535 DLG4 / P78352 / discs large MAGUK scaffold protein 4  / reaction / complex
 ENSG00000152413 HOMER1 / Q86YM7 / homer scaffolding protein 1  / complex / reaction
 ENSG00000103942 HOMER2 / Q9NSB8 / homer scaffolding protein 2  / complex / reaction
 ENSG00000170579 DLGAP1 / O14490 / DLG associated protein 1  / complex / reaction
 ENSG00000080845 DLGAP4 / Q9Y2H0 / DLG associated protein 4  / reaction / complex
 ENSG00000162105 Q9UPX8 / SHANK2 / SH3 and multiple ankyrin repeat domains 2  / complex / reaction
 ENSG00000198010 DLGAP2 / Q9P1A6 / DLG associated protein 2  / complex / reaction






 

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