ENSG00000101335


Homo sapiens

Features
Gene ID: ENSG00000101335
  
Biological name :MYL9
  
Synonyms : MYL9 / myosin light chain 9 / P24844
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.23
Gene start: 36541484
Gene end: 36551447
  
Corresponding Affymetrix probe sets: 201058_s_at (Human Genome U133 Plus 2.0 Array)   244149_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000217313
Ensembl peptide - ENSP00000279022
NCBI entrez gene - 10398     See in Manteia.
OMIM - 609905
RefSeq - NM_006097
RefSeq - NM_181526
RefSeq Peptide - NP_006088
RefSeq Peptide - NP_852667
swissprot - P24844
Ensembl - ENSG00000101335
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DLGAP4 / Q9Y2H0 / DLG associated protein 4ENSG0000008084512
DLGAP2 / Q9P1A6 / DLG associated protein 2ENSG000001980109
DLGAP3 / O95886 / DLG associated protein 3ENSG000001165449
DLGAP1 / O14490 / DLG associated protein 1ENSG000001705798
DLGAP5 / Q15398 / DLG associated protein 5ENSG000001267874


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0006937 regulation of muscle contraction TAS
 biological_processGO:0045652 regulation of megakaryocyte differentiation TAS
 biological_processGO:0070527 platelet aggregation HMP
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005859 muscle myosin complex TAS
 cellular_componentGO:0016459 myosin complex IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008307 structural constituent of muscle TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
EPHA-mediated growth cone collapse
Sema4D induced cell migration and growth-cone collapse
Smooth Muscle Contraction
RHO GTPases activate PKNs
RHO GTPases activate CIT
RHO GTPases Activate ROCKs
RHO GTPases activate PAKs
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000058272 O14974 / PPP1R12A / protein phosphatase 1 regulatory subunit 12A  / reaction
 ENSG00000122966 CIT / O14578 / citron rho-interacting serine/threonine kinase  / reaction
 ENSG00000067560 RHOA / P61586 / ras homolog family member A  / reaction
 ENSG00000134318 ROCK2 / O75116 / Rho associated coiled-coil containing protein kinase 2  / reaction
 ENSG00000077157 O60237 / PPP1R12B / protein phosphatase 1 regulatory subunit 12B  / reaction
 ENSG00000143878 RHOB / P62745 / ras homolog family member B  / reaction
 ENSG00000092841 MYL6 / P60660 / myosin light chain 6  / complex
 ENSG00000133392 MYH11 / P35749 / myosin heavy chain 11  / complex
 ENSG00000100345 MYH9 / P35579 / myosin heavy chain 9  / complex
 ENSG00000133026 MYH10 / P35580 / myosin heavy chain 10  / complex
 ENSG00000101335 MYL9 / P24844 / myosin light chain 9  / complex
 ENSG00000105357 MYH14 / Q7Z406 / myosin heavy chain 14  / complex
 ENSG00000118680 MYL12B / O14950 / myosin light chain 12B  / complex
 ENSG00000213639 P62140 / PPP1CB / protein phosphatase 1 catalytic subunit beta  / reaction
 ENSG00000155366 RHOC / P08134 / ras homolog family member C  / reaction
 ENSG00000180370 PAK2 / Q13177 / p21 (RAC1) activated kinase 2  / reaction
 ENSG00000065534 MYLK / Q15746 / myosin light chain kinase  / reaction
 ENSG00000198668 CALM1 / P0DP23 / calmodulin 1  / reaction
 ENSG00000067900 ROCK1 / Q13464 / Rho associated coiled-coil containing protein kinase 1  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr