ENSMUSG00000004341


Mus musculus

Features
Gene ID: ENSMUSG00000004341
  
Biological name :Gpx6
  
Synonyms : Glutathione peroxidase 6 / Gpx6 / Q91WR8
  
Possible biological names infered from orthology : P59796
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.1
Gene start: 21312125
Gene end: 21319624
  
Corresponding Affymetrix probe sets: 10403911 (MoGene1.0st)   1452135_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000004453
NCBI entrez gene - 75512     See in Manteia.
MGI - MGI:1922762
RefSeq - XM_011244355
RefSeq - NM_145451
RefSeq - XM_006516797
RefSeq Peptide - NP_663426
swissprot - Q91WR8
Ensembl - ENSMUSG00000004341
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpx3ENSDARG00000043342Danio rerio
 GPX3ENSGALG00000004521Gallus gallus
 GPX6ENSG00000198704Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gpx3 / P46412 / Glutathione peroxidase 3 / P22352*ENSMUSG0000001833967
Gpx5 / P21765 / Epididymal secretory glutathione peroxidase / O75715* / glutathione peroxidase 5*ENSMUSG0000000434464
Gpx1 / P11352 / Mus musculus glutathione peroxidase 1 (Gpx1), transcript variant 2, mRNA. / P07203* / glutathione peroxidase 1*ENSMUSG0000006385644
Gpx2 / glutathione peroxidase 2 / P18283*ENSMUSG0000004280838
Gpx7 / Q99LJ6 / Glutathione peroxidase 7 / Q96SL4*ENSMUSG0000002859729
Gpx8 / Q9D7B7 / Probable glutathione peroxidase 8 / Q8TED1* / glutathione peroxidase 8 (putative)*ENSMUSG0000002176026
Gpx4 / O70325 / Phospholipid hydroperoxide glutathione peroxidase, mitochondrial / P36969* / glutathione peroxidase 4*ENSMUSG0000007570625


Protein motifs (from Interpro)
Interpro ID Name
 IPR000889  Glutathione peroxidase
 IPR029759  Glutathione peroxidase active site
 IPR029760  Glutathione peroxidase conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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