ENSG00000198704


Homo sapiens

Features
Gene ID: ENSG00000198704
  
Biological name :GPX6
  
Synonyms : glutathione peroxidase 6 / GPX6 / P59796
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p22.1
Gene start: 28503296
Gene end: 28528215
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000354581
Ensembl peptide - ENSP00000483462
Ensembl peptide - ENSP00000417364
NCBI entrez gene - 257202     See in Manteia.
OMIM - 607913
RefSeq - NM_182701
RefSeq Peptide - NP_874360
swissprot - A0A182DWH6
swissprot - A0A087X0K3
swissprot - P59796
Ensembl - ENSG00000198704
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpx3ENSDARG00000043342Danio rerio
 GPX3ENSGALG00000004521Gallus gallus
 Gpx6ENSMUSG00000004341Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPX3 / P22352 / glutathione peroxidase 3ENSG0000021144570
GPX5 / O75715 / glutathione peroxidase 5ENSG0000022458667
GPX1 / P07203 / glutathione peroxidase 1ENSG0000023327635
GPX2 / P18283 / glutathione peroxidase 2ENSG0000017615334
GPX7 / Q96SL4 / glutathione peroxidase 7ENSG0000011615725
GPX8 / Q8TED1 / glutathione peroxidase 8 (putative)ENSG0000016429424
GPX4 / P36969 / glutathione peroxidase 4ENSG0000016746823


Protein motifs (from Interpro)
Interpro ID Name
 IPR000889  Glutathione peroxidase
 IPR029759  Glutathione peroxidase active site
 IPR029760  Glutathione peroxidase conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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