ENSMUSG00000004371


Mus musculus

Features
Gene ID: ENSMUSG00000004371
  
Biological name :Il11
  
Synonyms : Il11 / Interleukin-11 / P47873
  
Possible biological names infered from orthology : P20809
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A1
Gene start: 4772373
Gene end: 4782857
  
Corresponding Affymetrix probe sets: 10559667 (MoGene1.0st)   1449982_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092492
Ensembl peptide - ENSMUSP00000131168
NCBI entrez gene - 16156     See in Manteia.
MGI - MGI:107613
RefSeq - XM_017321988
RefSeq - NM_001290423
RefSeq - NM_008350
RefSeq Peptide - NP_001277352
RefSeq Peptide - NP_032376
swissprot - A3KPB8
swissprot - F7A7F2
swissprot - P47873
Ensembl - ENSMUSG00000004371
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL11ENSG00000095752Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR020412  Interleukin-11, mammalian
 IPR020438  Interleukin-11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046888 negative regulation of hormone secretion ISO
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005142 interleukin-11 receptor binding IPI
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024789 Jak2 / Janus kinase 2 / O60674*  / complex / reaction
 ENSMUSG00000021756 Il6st / Q00560 / Interleukin-6 receptor subunit beta / P40189* / interleukin 6 signal transducer*  / reaction / complex
 ENSMUSG00000073889 Q64385 / Il11ra1 / Interleukin-11 receptor subunit alpha-1 / IL11RA* / Q14626* / interleukin 11 receptor subunit alpha*  / reaction / complex
 ENSMUSG00000028530 Jak1 / Janus kinase 1 / P23458*  / reaction / complex
 ENSMUSG00000078735 P70225 / Il11ra2 / Interleukin-11 receptor subunit alpha-2 / Q14626* / IL11RA* / interleukin 11 receptor subunit alpha*  / complex / reaction






 

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