ENSMUSG00000078735


Mus musculus

Features
Gene ID: ENSMUSG00000078735
  
Biological name :Il11ra2
  
Synonyms : Il11ra2 / Interleukin-11 receptor subunit alpha-2 / P70225
  
Possible biological names infered from orthology : IL11RA / interleukin 11 receptor subunit alpha / Q14626
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A5
Gene start: 42656355
Gene end: 42661893
  
Corresponding Affymetrix probe sets: 10504106 (MoGene1.0st)   10512334 (MoGene1.0st)   10512356 (MoGene1.0st)   1417505_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103641
NCBI entrez gene - 16158     See in Manteia.
MGI - MGI:109123
RefSeq - NM_010550
RefSeq - XM_006537625
RefSeq Peptide - NP_034680
swissprot - P70225
Ensembl - ENSMUSG00000078735
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il11raENSDARG00000026736Danio rerio
 IL11RAENSGALG00000005848Gallus gallus
 IL11RAENSG00000137070Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P70225 / Gm13305 / predicted gene 13305 / Q14626* / IL11RA* / interleukin 11 receptor subunit alpha*ENSMUSG00000073876100
Q64385 / Il11ra1 / Interleukin-11 receptor subunit alpha-1 / IL11RA* / Q14626* / interleukin 11 receptor subunit alpha*ENSMUSG0000007388999
Il6ra / P22272 / Interleukin-6 receptor subunit alpha / IL6R* / P08887* / interleukin 6 receptor*ENSMUSG0000002794725
Cntfr / O88507 / Ciliary neurotrophic factor receptor subunit alpha / P26992* / ciliary neurotrophic factor receptor*ENSMUSG0000002844424
Ebi3 / O35228 / Interleukin-27 subunit beta / Q14213* / Epstein-Barr virus induced 3*ENSMUSG0000000320615


Protein motifs (from Interpro)
Interpro ID Name
 IPR003530  Long hematopoietin receptor, soluble alpha chain, conserved site
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024789 Jak2 / Janus kinase 2 / O60674*  / reaction / complex
 ENSMUSG00000021756 Il6st / Q00560 / Interleukin-6 receptor subunit beta / P40189* / interleukin 6 signal transducer*  / complex / reaction
 ENSMUSG00000028530 Jak1 / Janus kinase 1 / P23458*  / complex / reaction
 ENSMUSG00000004371 Il11 / P47873 / Interleukin-11 / P20809*  / reaction / complex






 

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