ENSMUSG00000006216


Mus musculus

Features
Gene ID: ENSMUSG00000006216
  
Biological name :Clcnkb
  
Synonyms : Chloride channel protein ClC-Kb / Clcnkb / Q9WUB6
  
Possible biological names infered from orthology : chloride voltage-gated channel Ka / chloride voltage-gated channel Kb / CLCNKA / P51800 / P51801
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 141404353
Gene end: 141416014
  
Corresponding Affymetrix probe sets: 10517924 (MoGene1.0st)   1450340_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000006378
Ensembl peptide - ENSMUSP00000101414
Ensembl peptide - ENSMUSP00000119059
NCBI entrez gene - 56365     See in Manteia.
MGI - MGI:1930643
RefSeq - XM_011250307
RefSeq - NM_019701
RefSeq - XM_006539066
RefSeq - XM_006539067
RefSeq Peptide - NP_062675
swissprot - F6RJZ6
swissprot - Q9WUB6
Ensembl - ENSMUSG00000006216
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clcnkENSDARG00000022560Danio rerio
 ENSGALG00000003713Gallus gallus
 CLCNKAENSG00000186510Homo sapiens
 CLCNKBENSG00000184908Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Clcnka / Q9WUB7 / Chloride channel protein ClC-Ka / CLCNKB* / P51800* / P51801* / chloride voltage-gated channel Kb* / chloride voltage-gated channel Ka*ENSMUSG0000003377084
Clcn2 / Q9R0A1 / Chloride channel protein 2 / P51788* / chloride voltage-gated channel 2*ENSMUSG0000002284343
Clcn1 / Q64347 / Chloride channel protein 1 / P35523* / chloride voltage-gated channel 1*ENSMUSG0000002986241
Clcn4 / Q61418 / Mus musculus chloride channel, voltage-sensitive 4 (Clcn4), transcript variant 7, mRNA. / P51793* / chloride voltage-gated channel 4*ENSMUSG0000000060522
Clcn3 / P51791 / H(+)/Cl(-) exchange transporter 3 / P51790* / chloride voltage-gated channel 3*ENSMUSG0000000431922
Clcn7 / O70496 / H(+)/Cl(-) exchange transporter 7 / P51798* / chloride voltage-gated channel 7*ENSMUSG0000003663622
Clcn5 / Q9WVD4 / H(+)/Cl(-) exchange transporter 5 / P51795* / chloride voltage-gated channel 5*ENSMUSG0000000431722
Clcn6 / O35454 / Chloride transport protein 6 / P51797* / chloride voltage-gated channel 6*ENSMUSG0000002901621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000644  CBS domain
 IPR001807  Chloride channel, voltage gated
 IPR002250  Chloride channel ClC-K
 IPR014743  Chloride channel, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005247 voltage-gated chloride channel activity IBA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025418 Bsnd / Q8VIM4 / Barttin / Q8WZ55* / barttin CLCNK type accessory beta subunit*  / complex






 

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