ENSMUSG00000010021


Mus musculus

Features
Gene ID: ENSMUSG00000010021
  
Biological name :Kif19a
  
Synonyms : Kif19a / Kinesin-like protein KIF19 / Q99PT9
  
Possible biological names infered from orthology : KIF19 / kinesin family member 19 / Q2TAC6
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 114765388
Gene end: 114790739
  
Corresponding Affymetrix probe sets: 10382409 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000122743
Ensembl peptide - ENSMUSP00000081398
Ensembl peptide - ENSMUSP00000115663
NCBI entrez gene - 286942     See in Manteia.
MGI - MGI:2447024
RefSeq - XM_006533507
RefSeq - NM_001102615
RefSeq Peptide - NP_001096085
swissprot - A9XMT8
swissprot - A2AC95
swissprot - Q99PT9
swissprot - F7BXY3
Ensembl - ENSMUSG00000010021
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif19ENSDARG00000053026Danio rerio
 KIF19ENSGALG00000004502Gallus gallus
 KIF19ENSG00000196169Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm4869ENSMUSG0000010635047
Kif18a / Q91WD7 / Kinesin-like protein KIF18A / Q8NI77* / kinesin family member 18A*ENSMUSG0000002711524
Kif18b / Q6PFD6 / Kinesin-like protein KIF18B / Q86Y91* / kinesin family member 18B*ENSMUSG0000005137823
Kif24 / Q6NWW5 / Kinesin-like protein KIF24 / Q5T7B8* / kinesin family member 24*ENSMUSG0000002843820
Kif22 / Q3V300 / Kinesin-like protein KIF22 / Q14807* / kinesin family member 22*ENSMUSG0000003067718
Kif20b / Q80WE4 / Kinesin-like protein KIF20B / Q96Q89* / kinesin family member 20B*ENSMUSG0000002479518
Kif23 / E9Q5G3 / Kinesin-like protein KIF23 / Q02241* / kinesin family member 23*ENSMUSG0000003225416
Kif2a / P28740 / Kinesin-like protein KIF2A / O00139* / kinesin family member 2A*ENSMUSG0000002169315
Kif2c / Q922S8 / Kinesin-like protein KIF2C / Q99661* / kinesin family member 2C*ENSMUSG0000002867814
Kif2b / Q8C0N1 / Kinesin-like protein KIF2B / Q8N4N8* / kinesin family member 2B*ENSMUSG0000004675513
Kif20a / P97329 / Kinesin-like protein KIF20A / O95235* / kinesin family member 20A*ENSMUSG0000000377913


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0060404 axonemal microtubule depolymerization IMP
 biological_processGO:0070462 plus-end specific microtubule depolymerization IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005930 axoneme IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IDA


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0002285 abnormal tracheal ciliated epithelium morphology "structural anomaly of the epithelial lining of the trachea which contains numerous ciliated cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology:ISBN 0-397-51047-0]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0003574 abnormal oviduct morphology "malformation of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0003699 abnormal female reproductive system physiology "anomaly in the function of the female organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0011050 abnormal respiratory motile cilium morphology "any structural anomaly of the multiple epithelial tiny, motile hair-like projections, which have a variable arrangement of axonemal microtubules, contains molecular motors, and beat with a characteristic whip-like pattern that promote transport of fluids and other cells across the epithelium of the respiratory tract" [GO:0031514, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0011056 abnormal brain ependyma motile cilium morphology "any structural anomaly of the tiny, motile hair-like projections from the epithelial cells that line the ventricles in the brain, which beat in concert and to move cerebrospinal fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

 MP:0011644 abnormal oviduct epithelium motile cilium morphology "any structural anomaly of the multiple epithelial tiny, motile hair-like projections, which have a variable arrangement of axonemal microtubules, contains molecular motors, and beat with a characteristic whip-like pattern that promote transport of fluids and other cells across the epithelium of the oviduct" [MGI:csmith]
Show

Allelic Composition: ApcMin/Apc+,Rr21tm1Jta/Rr21+
Genetic Background: involves: C57BL/6

Allelic Composition: Kif19atm1Noh/Kif19a+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr