ENSMUSG00000003779


Mus musculus

Features
Gene ID: ENSMUSG00000003779
  
Biological name :Kif20a
  
Synonyms : Kif20a / Kinesin-like protein KIF20A / P97329
  
Possible biological names infered from orthology : kinesin family member 20A / O95235
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B1
Gene start: 34624624
Gene end: 34633265
  
Corresponding Affymetrix probe sets: 10454709 (MoGene1.0st)   1449207_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130045
Ensembl peptide - ENSMUSP00000132659
NCBI entrez gene - 19348     See in Manteia.
MGI - MGI:1201682
RefSeq - NM_001166407
RefSeq - NM_001166406
RefSeq - NM_009004
RefSeq Peptide - NP_001159878
RefSeq Peptide - NP_001159879
RefSeq Peptide - NP_033030
swissprot - P97329
Ensembl - ENSMUSG00000003779
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif20aENSDARG00000044491Danio rerio
 KIF20AENSGALG00000035030Gallus gallus
 KIF20AENSG00000112984Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kif20b / Q80WE4 / Kinesin-like protein KIF20B / Q96Q89* / kinesin family member 20B*ENSMUSG0000002479533
Kif23 / E9Q5G3 / Kinesin-like protein KIF23 / Q02241* / kinesin family member 23*ENSMUSG0000003225418
Kif24 / Q6NWW5 / Kinesin-like protein KIF24 / Q5T7B8* / kinesin family member 24*ENSMUSG0000002843816
Gm4869ENSMUSG0000010635015
Q99PT9 / Kif19a / Kinesin-like protein KIF19 / KIF19* / Q2TAC6* / kinesin family member 19*ENSMUSG0000001002115
Kif18a / Q91WD7 / Kinesin-like protein KIF18A / Q8NI77* / kinesin family member 18A*ENSMUSG0000002711515
Kif22 / Q3V300 / Kinesin-like protein KIF22 / Q14807* / kinesin family member 22*ENSMUSG0000003067714
Kif18b / Q6PFD6 / Kinesin-like protein KIF18B / Q86Y91* / kinesin family member 18B*ENSMUSG0000005137814
Kif2c / Q922S8 / Kinesin-like protein KIF2C / Q99661* / kinesin family member 2C*ENSMUSG0000002867812
Kif2a / P28740 / Kinesin-like protein KIF2A / O00139* / kinesin family member 2A*ENSMUSG0000002169312
Kif2b / Q8C0N1 / Kinesin-like protein KIF2B / Q8N4N8* / kinesin family member 2B*ENSMUSG0000004675511


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027326  Kinesin-like protein KIF20A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis ISO
 biological_processGO:0000910 cytokinesis IEA
 biological_processGO:0000920 cell separation after cytokinesis ISS
 biological_processGO:0001578 microtubule bundle formation ISS
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032465 regulation of cytokinesis ISS
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005819 spindle ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030496 midbody ISO
 cellular_componentGO:0032154 cleavage furrow ISO
 cellular_componentGO:0045171 intercellular bridge ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003777 microtubule motor activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0019901 protein kinase binding ISO


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
COPI-dependent Golgi-to-ER retrograde traffic
Mitotic Telophase/Cytokinesis
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030867 Plk1 / Q07832 / polo like kinase 1 / P53350*  / reaction






 

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