ENSMUSG00000028678


Mus musculus

Features
Gene ID: ENSMUSG00000028678
  
Biological name :Kif2c
  
Synonyms : Kif2c / Kinesin-like protein KIF2C / Q922S8
  
Possible biological names infered from orthology : kinesin family member 2C / Q99661
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D1
Gene start: 117159639
Gene end: 117182639
  
Corresponding Affymetrix probe sets: 10515431 (MoGene1.0st)   1432392_at (Mouse Genome 430 2.0 Array)   1437611_x_at (Mouse Genome 430 2.0 Array)   1449060_at (Mouse Genome 430 2.0 Array)   1454221_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000064261
Ensembl peptide - ENSMUSP00000102044
Ensembl peptide - ENSMUSP00000122655
NCBI entrez gene - 73804     See in Manteia.
MGI - MGI:1921054
RefSeq - XM_017320411
RefSeq - NM_001290662
RefSeq - NM_134471
RefSeq - XM_006503433
RefSeq - XM_006503435
RefSeq - XM_011240620
RefSeq - XM_011240621
RefSeq - XM_011240622
RefSeq Peptide - NP_001277591
RefSeq Peptide - NP_608301
swissprot - Q3TTL2
swissprot - Q922S8
swissprot - A2AE72
Ensembl - ENSMUSG00000028678
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif2cENSDARG00000076228Danio rerio
 ENSGALG00000010120Gallus gallus
 KIF2CENSG00000142945Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kif2a / P28740 / Kinesin-like protein KIF2A / O00139* / kinesin family member 2A*ENSMUSG0000002169352
Kif2b / Q8C0N1 / Kinesin-like protein KIF2B / Q8N4N8* / kinesin family member 2B*ENSMUSG0000004675544
Kif24 / Q6NWW5 / Kinesin-like protein KIF24 / Q5T7B8* / kinesin family member 24*ENSMUSG0000002843833
Kif18a / Q91WD7 / Kinesin-like protein KIF18A / Q8NI77* / kinesin family member 18A*ENSMUSG0000002711521
Q99PT9 / Kif19a / Kinesin-like protein KIF19 / KIF19* / Q2TAC6* / kinesin family member 19*ENSMUSG0000001002119
Gm4869ENSMUSG0000010635019
Kif20b / Q80WE4 / Kinesin-like protein KIF20B / Q96Q89* / kinesin family member 20B*ENSMUSG0000002479519
Kif18b / Q6PFD6 / Kinesin-like protein KIF18B / Q86Y91* / kinesin family member 18B*ENSMUSG0000005137819
Kif23 / E9Q5G3 / Kinesin-like protein KIF23 / Q02241* / kinesin family member 23*ENSMUSG0000003225418
Kif22 / Q3V300 / Kinesin-like protein KIF22 / Q14807* / kinesin family member 22*ENSMUSG0000003067716
Kif20a / P97329 / Kinesin-like protein KIF20A / O95235* / kinesin family member 20A*ENSMUSG0000000377915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007019 microtubule depolymerization IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007080 mitotic metaphase plate congression IEA
 biological_processGO:0030951 establishment or maintenance of microtubule cytoskeleton polarity IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051310 metaphase plate congression IEA
 biological_processGO:0051315 attachment of mitotic spindle microtubules to kinetochore IEA
 biological_processGO:0051983 regulation of chromosome segregation IEA
 cellular_componentGO:0000775 chromosome, centromeric region ISO
 cellular_componentGO:0000776 kinetochore ISO
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005881 cytoplasmic microtubule ISS
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0035371 microtubule plus-end IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0051010 microtubule plus-end binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
COPI-dependent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028678 Kif2c / Q922S8 / Kinesin-like protein KIF2C / Q99661* / kinesin family member 2C*  / complex / reaction
 ENSMUSG00000021693 Kif2a / P28740 / Kinesin-like protein KIF2A / O00139* / kinesin family member 2A*  / reaction
 ENSMUSG00000046755 Kif2b / Q8C0N1 / Kinesin-like protein KIF2B / Q8N4N8* / kinesin family member 2B*  / reaction






 

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