Manteia

ENSMUSG00000030677

Mus musculus

Features

Gene ID:	ENSMUSG00000030677

Biological name :	Kif22

Synonyms :	Kif22 / Kinesin-like protein KIF22 / Q3V300

Possible biological names infered from orthology :	kinesin family member 22 / Q14807

Species:	Mus musculus

Chr. number:	7
Strand:	-1
Band:	F3
Gene start:	127027729
Gene end:	127042471

Corresponding Affymetrix probe sets:	10568150 (MoGene1.0st) 1423813_at (Mouse Genome 430 2.0 Array) 1437716_x_at (Mouse Genome 430 2.0 Array) 1451128_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000032915 Ensembl peptide - ENSMUSP00000145987 Ensembl peptide - ENSMUSP00000145752 NCBI entrez gene - 110033 See in Manteia. MGI - MGI:109233 RefSeq - NM_145588 RefSeq - XM_006507201 RefSeq Peptide - NP_663563 swissprot - A0A0U1RPH8 swissprot - Q3V300 swissprot - A0A0U1RNY7 Ensembl - ENSMUSG00000030677

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Kif18a / Q91WD7 / Kinesin-like protein KIF18A / Q8NI77* / kinesin family member 18A*	ENSMUSG00000027115	27
Q99PT9 / Kif19a / Kinesin-like protein KIF19 / KIF19* / Q2TAC6* / kinesin family member 19*	ENSMUSG00000010021	27
Gm4869	ENSMUSG00000106350	25
Kif18b / Q6PFD6 / Kinesin-like protein KIF18B / Q86Y91* / kinesin family member 18B*	ENSMUSG00000051378	24
Kif20b / Q80WE4 / Kinesin-like protein KIF20B / Q96Q89* / kinesin family member 20B*	ENSMUSG00000024795	23
Kif23 / E9Q5G3 / Kinesin-like protein KIF23 / Q02241* / kinesin family member 23*	ENSMUSG00000032254	21
Kif24 / Q6NWW5 / Kinesin-like protein KIF24 / Q5T7B8* / kinesin family member 24*	ENSMUSG00000028438	21
Kif20a / P97329 / Kinesin-like protein KIF20A / O95235* / kinesin family member 20A*	ENSMUSG00000003779	19
Kif2c / Q922S8 / Kinesin-like protein KIF2C / Q99661* / kinesin family member 2C*	ENSMUSG00000028678	18
Kif2a / P28740 / Kinesin-like protein KIF2A / O00139* / kinesin family member 2A*	ENSMUSG00000021693	17
Kif2b / Q8C0N1 / Kinesin-like protein KIF2B / Q8N4N8* / kinesin family member 2B*	ENSMUSG00000046755	16

Protein motifs (from Interpro)

Interpro ID	Name
IPR001752	Kinesin motor domain
IPR003583	Helix-hairpin-helix DNA-binding motif, class 1
IPR010994	RuvA domain 2-like
IPR019821	Kinesin motor domain, conserved site
IPR026986	Kinesin-like protein KIF22 (Kid)
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR027640	Kinesin-like protein
IPR036961	Kinesin motor domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006281	DNA repair	IEA
biological_process	GO:0007018	microtubule-based movement	IEA
biological_process	GO:0007062	sister chromatid cohesion	IEA
biological_process	GO:0007080	mitotic metaphase plate congression	IEA
biological_process	GO:0051310	metaphase plate congression	IEA
cellular_component	GO:0000785	chromatin	IDA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005819	spindle	IDA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005856	cytoskeleton	IEA
cellular_component	GO:0005871	kinesin complex	IBA
cellular_component	GO:0005874	microtubule	IEA
cellular_component	GO:0016607	nuclear speck	IEA
cellular_component	GO:0072686	mitotic spindle	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0003774	motor activity	IEA
molecular_function	GO:0003777	microtubule motor activity	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008017	microtubule binding	IEA
molecular_function	GO:0016887	ATPase activity	IBA

Pathways (from Reactome)

Pathway description

MHC class II antigen presentation

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001672	abnormal embryogenesis/ development	"anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gria1^tm1Erk/Gria1^tm1Erk Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gria1^tm1Erk/Gria1^tm1Erk Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0003702	abnormal chromosome morphology	"anomalies in the structure of the compact, intertwined molecules of DNA found in the nucleus which carry genetic information " [hdene:Howard Dene , Mouse Genome Informatics Curator]	Show Allelic Composition: Gria1^tm1Erk/Gria1^tm1Erk Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0011104	partial embryonic lethality before implantation	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]	Show Allelic Composition: Gria1^tm1Erk/Gria1^tm1Erk Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000030677	Kif22 / Q3V300 / Kinesin-like protein KIF22 / Q14807* / kinesin family member 22*	/ complex / reaction
ENSMUSG00000034311	Kif4 / P33174 / Chromosome-associated kinesin KIF4 / KIF4A* / KIF4B* / Q2VIQ3* / O95239* / kinesin family member 4B* / kinesin family member 4A*	/ reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr