ENSMUSG00000021541


Mus musculus

Features
Gene ID: ENSMUSG00000021541
  
Biological name :Trpc7
  
Synonyms : Q9WVC5 / transient receptor potential cation channel, subfamily C, member 7 / Trpc7
  
Possible biological names infered from orthology : Q9HCX4
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B1
Gene start: 56773113
Gene end: 56895789
  
Corresponding Affymetrix probe sets: 10409602 (MoGene1.0st)   1420561_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134481
Ensembl peptide - ENSMUSP00000134285
Ensembl peptide - ENSMUSP00000134662
Ensembl peptide - ENSMUSP00000022023
Ensembl peptide - ENSMUSP00000105497
Ensembl peptide - ENSMUSP00000119809
Ensembl peptide - ENSMUSP00000133305
Ensembl peptide - ENSMUSP00000133411
NCBI entrez gene - 26946     See in Manteia.
MGI - MGI:1349470
RefSeq - XM_006517264
RefSeq - NM_001302372
RefSeq - NM_001302373
RefSeq - NM_012035
RefSeq - XM_006517262
RefSeq - XM_006517263
RefSeq Peptide - NP_036165
RefSeq Peptide - NP_001289301
RefSeq Peptide - NP_001289302
swissprot - D6RI84
swissprot - G3UWI6
swissprot - G3UWT1
swissprot - G3UYZ6
swissprot - G3UZF9
swissprot - E9PVJ9
swissprot - G3UZW6
swissprot - Q0VFY2
swissprot - Q9WVC5
Ensembl - ENSMUSG00000021541
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trpc7aENSDARG00000027523Danio rerio
 trpc7bENSDARG00000079469Danio rerio
 TRPC7ENSGALG00000006297Gallus gallus
 TRPC7ENSG00000069018Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trpc3 / transient receptor potential cation channel, subfamily C, member 3 / Q13507*ENSMUSG0000002771678
Trpc6 / Q61143 / transient receptor potential cation channel, subfamily C, member 6 / Q9Y210*ENSMUSG0000003199774
Trpc4 / Q9QUQ5 / transient receptor potential cation channel, subfamily C, member 4 / Q9UBN4*ENSMUSG0000002774837
Trpc5 / Q9QX29 / transient receptor potential cation channel, subfamily C, member 5 / Q9UL62*ENSMUSG0000004171036
Xntrpc / Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthroughENSMUSG0000007042534
Trpc2 / Q9R244 / Short transient receptor potential channel 2 ENSMUSG0000010025433
Trpc1 / transient receptor potential cation channel, subfamily C, member 1 / P48995*ENSMUSG0000003283932


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR002153  Transient receptor potential channel, canonical
 IPR004729  Transient receptor potential channel
 IPR005463  Transient receptor potential channel, canonical 7
 IPR005821  Ion transport domain
 IPR013555  Transient receptor ion channel domain
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006828 manganese ion transport IDA
 biological_processGO:0007338 single fertilization IBA
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005801 cis-Golgi network IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0015279 store-operated calcium channel activity IBA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis
Elevation of cytosolic Ca2+ levels
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: C4btm1Crr/C4btm1Crr
Genetic Background: involves: 129S4/SvJae

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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