ENSMUSG00000032839


Mus musculus

Features
Gene ID: ENSMUSG00000032839
  
Biological name :Trpc1
  
Synonyms : transient receptor potential cation channel, subfamily C, member 1 / Trpc1
  
Possible biological names infered from orthology : P48995
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.3
Gene start: 95705082
Gene end: 95750375
  
Corresponding Affymetrix probe sets: 10595753 (MoGene1.0st)   1421095_a_at (Mouse Genome 430 2.0 Array)   1421096_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057640
Ensembl peptide - ENSMUSP00000140994
Ensembl peptide - ENSMUSP00000140550
Ensembl peptide - ENSMUSP00000139672
Ensembl peptide - ENSMUSP00000139577
NCBI entrez gene - 22063     See in Manteia.
MGI - MGI:109528
RefSeq - XM_006511057
RefSeq - NM_001311123
RefSeq - NM_011643
RefSeq - XM_006511053
RefSeq - XM_006511055
RefSeq - XM_006511056
RefSeq Peptide - NP_001298052
RefSeq Peptide - NP_035773
swissprot - B7ZMP6
swissprot - A0A087WP07
swissprot - B2RPS7
swissprot - A0A087WRB2
swissprot - A0A087WSD0
Ensembl - ENSMUSG00000032839
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trpc1ENSDARG00000061203Danio rerio
 TRPC1ENSGALG00000002639Gallus gallus
 TRPC1ENSG00000144935Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trpc4 / Q9QUQ5 / transient receptor potential cation channel, subfamily C, member 4 / Q9UBN4*ENSMUSG0000002774844
Trpc5 / Q9QX29 / transient receptor potential cation channel, subfamily C, member 5 / Q9UL62*ENSMUSG0000004171042
Trpc6 / Q61143 / transient receptor potential cation channel, subfamily C, member 6 / Q9Y210*ENSMUSG0000003199735
Trpc3 / transient receptor potential cation channel, subfamily C, member 3 / Q13507*ENSMUSG0000002771634
Trpc7 / Q9WVC5 / transient receptor potential cation channel, subfamily C, member 7 / Q9HCX4*ENSMUSG0000002154134
Xntrpc / Xndc1-transient receptor potential cation channel, subfamily C, member 2 readthroughENSMUSG0000007042530
Trpc2 / Q9R244 / Short transient receptor potential channel 2 ENSMUSG0000010025429


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR002153  Transient receptor potential channel, canonical
 IPR004729  Transient receptor potential channel
 IPR005457  Transient receptor potential channel, canonical 1
 IPR005821  Ion transport domain
 IPR013555  Transient receptor ion channel domain
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0042438 melanin biosynthetic process IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0070679 inositol 1,4,5 trisphosphate binding IEA


Pathways (from Reactome)
Pathway description
TRP channels
Ion homeostasis
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000623 reduced salivation "decrease flow, secretion, or amount of saliva" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Apptm1Somm/Apptm1Somm
Genetic Background: C57BL/6-Apptm1Somm

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Enahtm1Fbg/Enahtm1Fbg,Evltm1Fbg/Evltm1Fbg,Vasptm1Ref/Vasptm1Ref
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0001264 increased body size "larger than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
Show

Allelic Composition: Enahtm1Fbg/Enahtm1Fbg,Evltm1Fbg/Evltm1Fbg,Vasptm1Ref/Vasptm1Ref
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0003463 abnormal single cell response "altered values from controls obtained upon extra- or intracellular recordings from single cells" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Trpc5tm1.1Lbi/Y
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

Allelic Composition: Trpc1tm1Lbi/Trpc1tm1Lbi,Trpc4tm1Bni/Trpc4tm1Bni
Genetic Background: involves: 129 * C57BL/6

 MP:0013300 abnormal submandibular gland physiology "any functional anomaly of either of the large major salivary glands situated beneath the mandible" [MGI:Anna]
Show

Allelic Composition: Apptm1Somm/Apptm1Somm
Genetic Background: C57BL/6-Apptm1Somm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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