ENSMUSG00000022240


Mus musculus

Features
Gene ID: ENSMUSG00000022240
  
Biological name :Ctnnd2
  
Synonyms : catenin delta-2 isoform 2 / Ctnnd2
  
Possible biological names infered from orthology : catenin delta 2 / Q9UQB3
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: B2
Gene start: 30172593
Gene end: 31029341
  
Corresponding Affymetrix probe sets: 10423471 (MoGene1.0st)   1422592_at (Mouse Genome 430 2.0 Array)   1438891_at (Mouse Genome 430 2.0 Array)   1456116_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000154219
Ensembl peptide - ENSMUSP00000154410
Ensembl peptide - ENSMUSP00000154324
Ensembl peptide - ENSMUSP00000080427
NCBI entrez gene - 18163     See in Manteia.
MGI - MGI:1195966
RefSeq - XM_006520032
RefSeq - XM_006520033
RefSeq - NM_008729
RefSeq Peptide - NP_001342431
RefSeq Peptide - NP_032755
swissprot - E9QKH8
swissprot - B7ZNF6
Ensembl - ENSMUSG00000022240
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctnnd2aENSDARG00000062415Danio rerio
 ctnnd2bENSDARG00000003779Danio rerio
 CTNND2ENSGALG00000013001Gallus gallus
 CTNND2ENSG00000169862Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pkp4 / Q68FH0 / plakophilin 4 / Q99569*ENSMUSG0000002699149
Arvcf / P98203 / Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog / O00192* / ARVCF, delta catenin family member*ENSMUSG0000000032528
Ctnnd1 / P30999 / Mus musculus catenin (cadherin associated protein), delta 1 (Ctnnd1), transcript variant 7, mRNA. / O60716* / catenin delta 1*ENSMUSG0000003410127
P30999 / Gm28635 / predicted gene 28635 / O60716* / CTNND1* / catenin delta 1*ENSMUSG0000010164527
Pkp3 / Q9QY23 / Plakophilin-3 / Q9Y446*ENSMUSG0000005406518
Pkp2 / plakophilin 2 / Q99959*ENSMUSG0000004195718
Pkp1 / P97350 / Plakophilin-1 / Q13835*ENSMUSG0000002641316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR028435  Plakophilin/Delta catenin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0060997 dendritic spine morphogenesis IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0001454 abnormal cued conditioning behavior "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0001469 abnormal contextual conditioning "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), or the environmental context in this case)" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0002207 abnormal long term potentiation "alterations in a persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pax3Sp-7H/Pax3Sp-7H
Genetic Background: involves: C3H/HeH * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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