Manteia

ENSMUSG00000024459

Mus musculus

Features

Gene ID:	ENSMUSG00000024459

Biological name :	H2-M5

Synonyms :	H2-M5

Possible biological names infered from orthology :	HLA-A / HLA-B / HLA-C / HLA-E / HLA-F / HLA-G / major histocompatibility complex, class I, A / major histocompatibility complex, class I, B / major histocompatibility complex, class I, C / major histocompatibility complex, class I, E / major histocompatibility complex, class I, F / major histocompatibility complex, class I, G / P01889 / P04439 / P10321 / P13746 / P16188 / P17693 / P30480 / P30486 / P30511 / Q29836 / Q31610 / Q31612

Species:	Mus musculus

Chr. number:	17
Strand:	-1
Band:	B1
Gene start:	36984061
Gene end:	36989537

Corresponding Affymetrix probe sets:	10450843 (MoGene1.0st)

Cross references:	Ensembl peptide - ENSMUSP00000131365 Ensembl peptide - ENSMUSP00000109297 Ensembl peptide - ENSMUSP00000134912 Ensembl peptide - ENSMUSP00000135262 NCBI entrez gene - 240095 See in Manteia. MGI - MGI:95917 RefSeq - NM_001115075 RefSeq Peptide - NP_001108547 swissprot - H3BK58 swissprot - H3BJA9 swissprot - F6VXI7 swissprot - A7VMS3 Ensembl - ENSMUSG00000024459

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
HLA-A	ENSG00000206503	Homo sapiens
HLA-B	ENSG00000234745	Homo sapiens
HLA-C	ENSG00000204525	Homo sapiens
HLA-E	ENSG00000204592	Homo sapiens
HLA-F	ENSG00000204642	Homo sapiens
HLA-G	ENSG00000204632	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Gm8909 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major ...	ENSMUSG00000073402	55
H2-Q7 / P14429 / Mus musculus histocompatibility 2, Q region locus 9 (H2-Q9), mRNA. / HLA-B* / HLA-E* / HLA-F* / HLA-G* / HLA-C* / HLA-A* / Q31612* / P17693* / P30480* / P30486* / P30511* /...	ENSMUSG00000060550	54
H2-Q2 / histocompatibility 2, Q region locus 2 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...	ENSMUSG00000091705	54
H2-D1 / P01899 / H-2 class I histocompatibility antigen, D-B alpha chain / HLA-B* / HLA-C* / HLA-A* / HLA-F* / HLA-G* / HLA-E* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* /...	ENSMUSG00000073411	53
H2-Q10 / P01898 / H-2 class I histocompatibility antigen, Q10 alpha chain / HLA-B* / HLA-C* / HLA-A* / HLA-F* / HLA-G* / HLA-E* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* ...	ENSMUSG00000067235	53
H2-Q1 / Mus musculus histocompatibility 2, Q region locus 1 (H2-Q1), transcript variant 2, mRNA. / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / HLA-A* / Q31612* / P17693* / P30480* / P30486...	ENSMUSG00000079507	53
H2-K1 / P01901 / histocompatibility 2, K1, K region / HLA-B* / HLA-C* / HLA-A* / HLA-F* / HLA-G* / HLA-E* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P...	ENSMUSG00000061232	53
H2-T23 / P06339 / H-2 class I histocompatibility antigen, D-37 alpha chain / HLA-B* / HLA-C* / HLA-A* / HLA-F* / HLA-G* / HLA-E* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836*...	ENSMUSG00000067212	52
H2-Q4 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...	ENSMUSG00000035929	52
Gm11127 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major...	ENSMUSG00000079492	51
H2-M2 / Mus musculus histocompatibility 2, M region locus 2 (H2-M2), transcript variant 2, mRNA. / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / HLA-A* / Q31612* / P17693* / P30480* / P30486...	ENSMUSG00000016283	51
H2-Q6 / histocompatibility 2, Q region locus 6 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...	ENSMUSG00000073409	51
H2-M3 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...	ENSMUSG00000016206	50
H2-T3 / histocompatibility 2, T region locus 3 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...	ENSMUSG00000054128	48
Gm7030 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major ...	ENSMUSG00000092243	47
H2-M1 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...	ENSMUSG00000037334	42
H2-M9 / histocompatibility 2, M region locus 9 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...	ENSMUSG00000067201	42
H2-M11 / histocompatibility 2, M region locus 11 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04...	ENSMUSG00000037537	42
H2-Bl / histocompatibility 2, blastocyst / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P...	ENSMUSG00000073406	30
H2-Q5 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...	ENSMUSG00000055413	29

Protein motifs (from Interpro)

Interpro ID	Name
IPR001039	MHC class I alpha chain, alpha1 alpha2 domains
IPR003006	Immunoglobulin/major histocompatibility complex, conserved site
IPR003597	Immunoglobulin C1-set
IPR007110	Immunoglobulin-like domain
IPR011161	MHC class I-like antigen recognition-like
IPR011162	MHC classes I/II-like antigen recognition protein
IPR013783	Immunoglobulin-like fold
IPR036179	Immunoglobulin-like domain superfamily
IPR037055	MHC class I-like antigen recognition-like superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	IBA
cellular_component	GO:0005886	plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005102	signaling receptor binding	IBA
molecular_function	GO:0042605	peptide antigen binding	IBA

Pathways (from Reactome)

Pathway description

ER-Phagosome pathway

Endosomal/Vacuolar pathway

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Neutrophil degranulation

Antigen Presentation: Folding, assembly and peptide loading of class I MHC

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002833	increased heart weight	"greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]	Show Allelic Composition: Gys2^{tm1a(KOMP)Wtsi}/Gys2^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Gys2^{tm1a(KOMP)Wtsi}/Wtsi
MP:0003960	increased lean body mass	"more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]	Show Allelic Composition: Gys2^{tm1a(KOMP)Wtsi}/Gys2^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Gys2^{tm1a(KOMP)Wtsi}/Wtsi
MP:0005561	increased mean corpuscular hemoglobin	"greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gys2^{tm1a(KOMP)Wtsi}/Gys2^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Gys2^{tm1a(KOMP)Wtsi}/Wtsi

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr