ENSMUSG00000067235


Mus musculus

Features
Gene ID: ENSMUSG00000067235
  
Biological name :H2-Q10
  
Synonyms : H-2 class I histocompatibility antigen, Q10 alpha chain / H2-Q10 / P01898
  
Possible biological names infered from orthology : HLA-A / HLA-B / HLA-C / HLA-E / HLA-F / HLA-G / major histocompatibility complex, class I, A / major histocompatibility complex, class I, B / major histocompatibility complex, class I, C / major histocompatibility complex, class I, E / major histocompatibility complex, class I, F / major histocompatibility complex, class I, G / P01889 / P04439 / P10321 / P13746 / P16188 / P17693 / P30480 / P30486 / P30511 / Q29836 / Q31610 / Q31612
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 35470089
Gene end: 35474563
  
Corresponding Affymetrix probe sets: 10444841 (MoGene1.0st)   1425137_a_at (Mouse Genome 430 2.0 Array)   1430802_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066419
Ensembl peptide - ENSMUSP00000134163
NCBI entrez gene - 15007     See in Manteia.
MGI - MGI:95929
RefSeq - NM_010391
RefSeq Peptide - NP_034521
swissprot - P01898
Ensembl - ENSMUSG00000067235
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HLA-AENSG00000206503Homo sapiens
 HLA-BENSG00000234745Homo sapiens
 HLA-CENSG00000204525Homo sapiens
 HLA-EENSG00000204592Homo sapiens
 HLA-FENSG00000204642Homo sapiens
 HLA-GENSG00000204632Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
H2-D1 / P01899 / H-2 class I histocompatibility antigen, D-B alpha chain / HLA-B* / HLA-C* / HLA-A* / HLA-F* / HLA-G* / HLA-E* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* /...ENSMUSG0000007341182
Gm8909 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major ...ENSMUSG0000007340281
H2-K1 / P01901 / histocompatibility 2, K1, K region / HLA-B* / HLA-C* / HLA-A* / HLA-F* / HLA-G* / HLA-E* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P...ENSMUSG0000006123279
H2-Q6 / histocompatibility 2, Q region locus 6 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...ENSMUSG0000007340977
H2-Q7 / P14429 / Mus musculus histocompatibility 2, Q region locus 9 (H2-Q9), mRNA. / HLA-B* / HLA-E* / HLA-F* / HLA-G* / HLA-C* / HLA-A* / Q31612* / P17693* / P30480* / P30486* / P30511* /...ENSMUSG0000006055077
H2-Q1 / Mus musculus histocompatibility 2, Q region locus 1 (H2-Q1), transcript variant 2, mRNA. / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / HLA-A* / Q31612* / P17693* / P30480* / P30486...ENSMUSG0000007950777
H2-Q2 / histocompatibility 2, Q region locus 2 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...ENSMUSG0000009170576
H2-Q4 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...ENSMUSG0000003592976
H2-T23 / P06339 / H-2 class I histocompatibility antigen, D-37 alpha chain / HLA-B* / HLA-C* / HLA-A* / HLA-F* / HLA-G* / HLA-E* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836*...ENSMUSG0000006721272
Gm11127 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major...ENSMUSG0000007949267
H2-T3 / histocompatibility 2, T region locus 3 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...ENSMUSG0000005412866
Gm7030 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major ...ENSMUSG0000009224361
H2-M3 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...ENSMUSG0000001620661
H2-M2 / Mus musculus histocompatibility 2, M region locus 2 (H2-M2), transcript variant 2, mRNA. / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / HLA-A* / Q31612* / P17693* / P30480* / P30486...ENSMUSG0000001628360
H2-M5 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...ENSMUSG0000002445956
H2-Bl / histocompatibility 2, blastocyst / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P...ENSMUSG0000007340650
H2-Q5 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...ENSMUSG0000005541349
H2-M1 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439* / P10321* / P13746* / P16188* / major h...ENSMUSG0000003733446
H2-M11 / histocompatibility 2, M region locus 11 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04...ENSMUSG0000003753745
H2-M9 / histocompatibility 2, M region locus 9 / HLA-A* / HLA-B* / HLA-C* / HLA-E* / HLA-F* / HLA-G* / Q31612* / P17693* / P30480* / P30486* / P30511* / Q29836* / Q31610* / P01889* / P04439...ENSMUSG0000006720143


Protein motifs (from Interpro)
Interpro ID Name
 IPR001039  MHC class I alpha chain, alpha1 alpha2 domains
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011161  MHC class I-like antigen recognition-like
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037055  MHC class I-like antigen recognition-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002474 antigen processing and presentation of peptide antigen via MHC class I IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005797 Golgi medial cisterna ISO
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane TAS
 cellular_componentGO:0042612 MHC class I protein complex IEA
 cellular_componentGO:0070971 endoplasmic reticulum exit site ISO
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane TAS
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0030881 beta-2-microglobulin binding ISO
 molecular_functionGO:0042605 peptide antigen binding IBA
 molecular_functionGO:0042608 T cell receptor binding ISO
 molecular_functionGO:0046977 TAP binding ISO


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Endosomal/Vacuolar pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Neutrophil degranulation
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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