ENSMUSG00000026401


Mus musculus

Features
Gene ID: ENSMUSG00000026401
  
Biological name :Cd55b
  
Synonyms : Cd55b
  
Possible biological names infered from orthology : CD55 / CD55 molecule (Cromer blood group) / P08174
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E4
Gene start: 130388537
Gene end: 130423009
  
Corresponding Affymetrix probe sets: 10357480 (MoGene1.0st)   1419727_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113352
Ensembl peptide - ENSMUSP00000108107
NCBI entrez gene - 13137     See in Manteia.
MGI - MGI:104849
RefSeq - XM_017314396
RefSeq - NM_001317361
RefSeq - NM_007827
RefSeq - XM_011247917
RefSeq Peptide - NP_001304290
RefSeq Peptide - NP_031853
swissprot - E9QAP4
swissprot - E9Q731
Ensembl - ENSMUSG00000026401
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rca2.1ENSDARG00000056075Danio rerio
 rca2.2ENSDARG00000095512Danio rerio
 CD55ENSG00000196352Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cd55 / Q61475 / Complement decay-accelerating factor, GPI-anchored / P08174* / CD55 molecule (Cromer blood group)*ENSMUSG0000002639978
Zp3r / zona pellucida 3 receptorENSMUSG0000004255422
C4bp / P08607 / C4b-binding protein ENSMUSG0000002640521
Cfh / P06909 / Complement factor H / CFHR3* / CFHR4* / Q92496* / P08603* / Q02985* / complement factor H related 4* / complement factor H related 3*ENSMUSG0000002636518
Cd46 / O88174 / Membrane cofactor protein / P15529* / CD46 molecule*ENSMUSG0000001649317
F13b / Q07968 / Coagulation factor XIII B chain / P05160*ENSMUSG0000002636816
Apoh / Q01339 / Beta-2-glycoprotein 1 / P02749* / apolipoprotein H*ENSMUSG0000000004915
Gm4788 / complement factor H-related protein C isoform 2 / CFH* / CFHR4* / CFHR3* / Q92496* / P08603* / Q02985* / complement factor H* / complement factor H related 3* / complement factor ...ENSMUSG0000007059415
Selp / Q01102 / selectin, platelet / P16109* / selectin P*ENSMUSG0000002658013
Sele / selectin, endothelial cell / P16581* / selectin E*ENSMUSG0000002658212
Sell / P18337 / selectin, lymphocyte / P14151* / selectin L*ENSMUSG0000002658111
Cfhr2 / complement factor H-related 2 / CFH* / CFHR3* / CFHR4* / Q92496* / P08603* / Q02985* / complement factor H* / complement factor H related 4* / complement factor H related 3*ENSMUSG0000003389811
Cfhr1 / complement factor H-related 1 / CFHR5* / CFHR2* / P36980* / Q9BXR6* / Q03591* / BX248415.1* / complement factor H related 5* / complement factor H related 2*ENSMUSG0000005703710


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
Neutrophil degranulation
COPI-mediated anterograde transport
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005505 increased platelet count "greater than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Bach2tm1a(EUCOMM)Wtsi/Bach2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Bach2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0008075 decreased CD4-positive T cell number "reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Bach2tm1a(EUCOMM)Wtsi/Bach2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Bach2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Bach2tm1a(EUCOMM)Wtsi/Bach2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Bach2tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026399 Cd55 / Q61475 / Complement decay-accelerating factor, GPI-anchored / P08174* / CD55 molecule (Cromer blood group)*  / reaction
 ENSMUSG00000090231 Cfb / P04186 / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment / P00751* / AL645922.1* / complement factor B*  / complex / reaction
 ENSMUSG00000024164 C3 / P01027 / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acylation stimulating protein Complement C3b alpha chain Complement C3c alpha chain...  / complex / reaction
 ENSMUSG00000073418 C4b / P01029 / Complement C4-B Complement C4 beta chain Complement C4 alpha chain C4a anaphylatoxin Complement C4 gamma chain / C4A* / P0C0L4* / P0C0L5* / complement C4B (Chido blood group)...  / complex / reaction
 ENSMUSG00000024371 C2 / P21180 / Complement C2 Complement C2b fragment Complement C2a fragment / P06681* / complement C2*  / reaction / complex
 ENSMUSG00000026401 Cd55b / CD55* / P08174* / CD55 molecule (Cromer blood group)*  / reaction






 

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