ENSMUSG00000026470


Mus musculus

Features
Gene ID: ENSMUSG00000026470
  
Biological name :Stx6
  
Synonyms : Q9JKK1 / Stx6 / Syntaxin-6
  
Possible biological names infered from orthology : O43752
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: G3
Gene start: 155158715
Gene end: 155208256
  
Corresponding Affymetrix probe sets: 10350766 (MoGene1.0st)   1423038_at (Mouse Genome 430 2.0 Array)   1431646_a_at (Mouse Genome 430 2.0 Array)   1440585_at (Mouse Genome 430 2.0 Array)   1441133_at (Mouse Genome 430 2.0 Array)   1450844_at (Mouse Genome 430 2.0 Array)   1460004_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141362
Ensembl peptide - ENSMUSP00000142089
Ensembl peptide - ENSMUSP00000141976
Ensembl peptide - ENSMUSP00000027743
NCBI entrez gene - 58244     See in Manteia.
MGI - MGI:1926235
RefSeq - XM_006529766
RefSeq - XM_017321868
RefSeq - NM_021433
RefSeq Peptide - NP_067408
swissprot - Q9JKK1
swissprot - A0A0A6YXG0
swissprot - A0A0A6YW23
Ensembl - ENSMUSG00000026470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx6ENSDARG00000042742Danio rerio
 STX6ENSGALG00000003880Gallus gallus
 STX6ENSG00000135823Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR015260  Syntaxin 6, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006906 vesicle fusion ISO
 biological_processGO:0007032 endosome organization IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0032456 endocytic recycling ISO
 biological_processGO:0032880 regulation of protein localization ISO
 biological_processGO:0042147 retrograde transport, endosome to Golgi ISO
 biological_processGO:0048193 Golgi vesicle transport IEA
 biological_processGO:0048278 vesicle docking IBA
 biological_processGO:0090161 Golgi ribbon formation ISO
 biological_processGO:1903827 regulation of cellular protein localization IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane IEA
 cellular_componentGO:0031201 SNARE complex ISO
 cellular_componentGO:0032588 trans-Golgi network membrane IDA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0045335 phagocytic vesicle IMP
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0055037 recycling endosome ISO
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019905 syntaxin binding ISO


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006024 Napa / Q9DB05 / Alpha-soluble NSF attachment protein / P54920* / NSF attachment protein alpha*  / reaction / complex
 ENSMUSG00000034187 Nsf / P46460 / Vesicle-fusing ATPase / P46459* / N-ethylmaleimide sensitive factor, vesicle fusing ATPase*  / complex / reaction
 ENSMUSG00000026696 Vamp4 / O70480 / vesicle-associated membrane protein 4 / O75379*  / complex
 ENSMUSG00000027522 Stx16 / Q8BVI5 / syntaxin 16 / O14662* / STX16-NPEPL1* / STX16-NPEPL1 readthrough (NMD candidate)*  / complex
 ENSMUSG00000024983 Vti1a / O89116 / vesicle transport through interaction with t-SNAREs 1A / Q96AJ9*  / complex






 

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