ENSMUSG00000026696


Mus musculus

Features
Gene ID: ENSMUSG00000026696
  
Biological name :Vamp4
  
Synonyms : O70480 / Vamp4 / vesicle-associated membrane protein 4
  
Possible biological names infered from orthology : O75379
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H2.1
Gene start: 162570515
Gene end: 162599084
  
Corresponding Affymetrix probe sets: 10351119 (MoGene1.0st)   1422895_at (Mouse Genome 430 2.0 Array)   1422896_at (Mouse Genome 430 2.0 Array)   1434796_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142298
Ensembl peptide - ENSMUSP00000116376
Ensembl peptide - ENSMUSP00000121977
Ensembl peptide - ENSMUSP00000051544
Ensembl peptide - ENSMUSP00000114172
Ensembl peptide - ENSMUSP00000115133
NCBI entrez gene - 53330     See in Manteia.
MGI - MGI:1858730
RefSeq - XM_006496936
RefSeq - NM_001356526
RefSeq - NM_016796
RefSeq - XM_006496934
RefSeq - XM_006496935
RefSeq Peptide - NP_058076
RefSeq Peptide - NP_001334054
RefSeq Peptide - NP_001343455
RefSeq Peptide - NP_001343456
swissprot - Q8BSN6
swissprot - O70480
swissprot - A0A0A6YY66
Ensembl - ENSMUSG00000026696
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vamp4ENSDARG00000043510Danio rerio
 VAMP4ENSGALG00000031381Gallus gallus
 VAMP4ENSG00000117533Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vamp2 / P63044 / vesicle-associated membrane protein 2 / P63027* / AC129492.3*ENSMUSG0000002089426
Vamp1 / Q62442 / vesicle-associated membrane protein 1 / P23763*ENSMUSG0000003033724
Vamp3 / P63024 / vesicle-associated membrane protein 3 / Q15836*ENSMUSG0000002895523
Vamp8 / vesicle-associated membrane protein 8 / Q9BV40*ENSMUSG0000005073219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001388  Synaptobrevin
 IPR016444  Synaptobrevin/Vesicle-associated membrane protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization ISO
 biological_processGO:0006887 exocytosis IBA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0035493 SNARE complex assembly ISO
 biological_processGO:0042996 regulation of Golgi to plasma membrane protein transport IMP
 biological_processGO:0043001 Golgi to plasma membrane protein transport IMP
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 biological_processGO:0090161 Golgi ribbon formation ISO
 biological_processGO:1901998 toxin transport IMP
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0008021 synaptic vesicle IBA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane IEA
 cellular_componentGO:0031201 SNARE complex IDA
 cellular_componentGO:0045335 phagocytic vesicle IDA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IBA


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006024 Napa / Q9DB05 / Alpha-soluble NSF attachment protein / P54920* / NSF attachment protein alpha*  / complex / reaction
 ENSMUSG00000034187 Nsf / P46460 / Vesicle-fusing ATPase / P46459* / N-ethylmaleimide sensitive factor, vesicle fusing ATPase*  / reaction / complex
 ENSMUSG00000024983 Vti1a / O89116 / vesicle transport through interaction with t-SNAREs 1A / Q96AJ9*  / complex
 ENSMUSG00000026470 Stx6 / Q9JKK1 / Syntaxin-6 / O43752*  / complex
 ENSMUSG00000027522 Stx16 / Q8BVI5 / syntaxin 16 / O14662* / STX16-NPEPL1* / STX16-NPEPL1 readthrough (NMD candidate)*  / complex






 

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