ENSMUSG00000030337


Mus musculus

Features
Gene ID: ENSMUSG00000030337
  
Biological name :Vamp1
  
Synonyms : Q62442 / Vamp1 / vesicle-associated membrane protein 1
  
Possible biological names infered from orthology : P23763
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F2
Gene start: 125215551
Gene end: 125245964
  
Corresponding Affymetrix probe sets: 10541877 (MoGene1.0st)   1421862_a_at (Mouse Genome 430 2.0 Array)   1421863_at (Mouse Genome 430 2.0 Array)   1453647_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000063466
Ensembl peptide - ENSMUSP00000144835
Ensembl peptide - ENSMUSP00000098503
Ensembl peptide - ENSMUSP00000032487
NCBI entrez gene - 22317     See in Manteia.
MGI - MGI:1313276
RefSeq - NM_001080557
RefSeq - NM_009496
RefSeq Peptide - NP_001074026
RefSeq Peptide - NP_033522
swissprot - Q62442
swissprot - A0A0N4SUV3
swissprot - D3YTU0
Ensembl - ENSMUSG00000030337
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vamp1ENSDARG00000031283Danio rerio
 zgc:92912ENSDARG00000097576Danio rerio
 VAMP1ENSGALG00000022955Gallus gallus
 VAMP1ENSG00000139190Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vamp2 / P63044 / vesicle-associated membrane protein 2 / P63027* / AC129492.3*ENSMUSG0000002089480
Vamp3 / P63024 / vesicle-associated membrane protein 3 / Q15836*ENSMUSG0000002895562
Vamp4 / O70480 / vesicle-associated membrane protein 4 / O75379*ENSMUSG0000002669629
Vamp8 / vesicle-associated membrane protein 8 / Q9BV40*ENSMUSG0000005073228


Protein motifs (from Interpro)
Interpro ID Name
 IPR001388  Synaptobrevin
 IPR016444  Synaptobrevin/Vesicle-associated membrane protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IBA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0035493 SNARE complex assembly IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0035579 specific granule membrane ISO
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070821 tertiary granule membrane ISO
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0019905 syntaxin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0001504 abnormal posture "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
Show

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

Allelic Composition: Vamp1lew/Vamp1lew
Genetic Background: involves: C3H/HeSnJ * CAST/EiJ

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
Show

Allelic Composition: Vamp1lew/Vamp1lew
Genetic Background: involves: C3H/HeSnJ * CAST/EiJ

 MP:0001524 impaired limb coordination "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]
Show

Allelic Composition: Vamp1lew/Vamp1lew
Genetic Background: involves: C3H/HeSnJ * CAST/EiJ

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fcer2atm1Putt/Fcer2a+
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0002690 akinesia "absence of movement or loss of the ability to move such as temporary or prolonged paralysis or "freezing in place"" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:82238]
Show

Allelic Composition: Vamp1lew/Vamp1lew
Genetic Background: involves: C3H/HeSnJ * CAST/EiJ

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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