ENSMUSG00000026659


Mus musculus

Features
Gene ID: ENSMUSG00000026659
  
Biological name :Dusp12
  
Synonyms : Dusp12 / Mus musculus dual specificity phosphatase 12 (Dusp12), transcript variant 3, mRNA. / Q9D0T2
  
Possible biological names infered from orthology : dual specificity phosphatase 12 / Q9UNI6
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H3
Gene start: 170873498
Gene end: 170885540
  
Corresponding Affymetrix probe sets: 10360003 (MoGene1.0st)   1420636_a_at (Mouse Genome 430 2.0 Array)   1441436_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130683
Ensembl peptide - ENSMUSP00000129530
Ensembl peptide - ENSMUSP00000130507
Ensembl peptide - ENSMUSP00000027970
Ensembl peptide - ENSMUSP00000044320
Ensembl peptide - ENSMUSP00000126676
Ensembl peptide - ENSMUSP00000129515
NCBI entrez gene - 80915     See in Manteia.
MGI - MGI:1890614
RefSeq - XM_006497042
RefSeq - NM_001356486
RefSeq - NM_023173
RefSeq Peptide - NP_001343415
RefSeq Peptide - NP_075662
swissprot - Q9D0T2
swissprot - E9PUU1
swissprot - Q4KL39
swissprot - Q924M1
swissprot - F6ZTK6
swissprot - G3UW79
swissprot - F7BAT9
swissprot - F6QRT3
Ensembl - ENSMUSG00000026659
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dusp12ENSDARG00000076330Danio rerio
 DUSP12ENSGALG00000007084Gallus gallus
 DUSP12ENSG00000081721Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dusp27 / Q148W8 / Inactive dual specificity phosphatase 27 / Q5VZP5* / dual specificity phosphatase 27, atypical*ENSMUSG0000002656422
Q60969 / Gm14698 / predicted gene 14698 / STYX* / Q8WUJ0* / serine/threonine/tyrosine interacting protein*ENSMUSG0000007174817
Styx / Q60969 / serine/threonine/tyrosine interaction protein / Q8WUJ0* / serine/threonine/tyrosine interacting protein*ENSMUSG0000005320517
Dusp19 / dual specificity phosphatase 19 / Q8WTR2*ENSMUSG0000002700115
Dusp15 / Q8R4V2 / Dual specificity protein phosphatase 15 / Q9H1R2* / dual specificity phosphatase 15*ENSMUSG0000004266215
Dusp26 / Q9D700 / Mus musculus dual specificity phosphatase 26 (putative) (Dusp26), transcript variant 2, mRNA. / Q9BV47* / dual specificity phosphatase 26*ENSMUSG0000003966115
Dusp28 / Q8BTR5 / Dual specificity phosphatase 28 / Q4G0W2*ENSMUSG0000004706714
Dusp14 / Q9JLY7 / Dual specificity protein phosphatase 14 / O95147* / dual specificity phosphatase 14*ENSMUSG0000001864814
Dusp3 / Q9D7X3 / Dual specificity protein phosphatase 3 / P51452* / dual specificity phosphatase 3*ENSMUSG0000000351814
Dusp22 / Q99N11 / Dual specificity protein phosphatase 22 / Q9NRW4* / dual specificity phosphatase 22*ENSMUSG0000006925514
Q9QYJ7 / Dusp13 / Q6B8I0 / Dual specificity protein phosphatase 13 isoform A / Q9UII6* / Q6B8I1* / dual specificity phosphatase 13*ENSMUSG0000002176814
Dusp18 / Q8VE01 / Dual specificity protein phosphatase 18 / Q8NEJ0* / dual specificity phosphatase 18*ENSMUSG0000004720513
Dupd1 / Q8BK84 / Dual specificity phosphatase DUPD1 / Q68J44* / dual specificity phosphatase and pro isomerase domain containing 1*ENSMUSG0000006382113
Dusp21 / Q9D9D8 / Dual specificity phosphatase 21 / Q9H596*ENSMUSG0000002504313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016278  Dual specificity protein phosphatase 12
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0033133 positive regulation of glucokinase activity IBA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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