ENSG00000081721


Homo sapiens

Features
Gene ID: ENSG00000081721
  
Biological name :DUSP12
  
Synonyms : dual specificity phosphatase 12 / DUSP12 / Q9UNI6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.3
Gene start: 161749758
Gene end: 161757238
  
Corresponding Affymetrix probe sets: 218576_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356920
Ensembl peptide - ENSP00000476528
Ensembl peptide - ENSP00000476912
Ensembl peptide - ENSP00000477122
NCBI entrez gene - 11266     See in Manteia.
OMIM - 604835
RefSeq - XM_005244862
RefSeq - NM_007240
RefSeq Peptide - NP_009171
swissprot - Q9UNI6
swissprot - V9GY92
swissprot - V9GYV5
Ensembl - ENSG00000081721
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dusp12ENSDARG00000076330Danio rerio
 DUSP12ENSGALG00000007084Gallus gallus
 Dusp12ENSMUSG00000026659Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP27 / Q5VZP5 / dual specificity phosphatase 27, atypicalENSG0000019884223
STYX / Q8WUJ0 / serine/threonine/tyrosine interacting proteinENSG0000019825216
DUSP19 / Q8WTR2 / dual specificity phosphatase 19ENSG0000016299915
DUSP15 / Q9H1R2 / dual specificity phosphatase 15ENSG0000014959915
DUSP28 / Q4G0W2 / dual specificity phosphatase 28ENSG0000018854215
DUSP26 / Q9BV47 / dual specificity phosphatase 26ENSG0000013387814
DUSP18 / Q8NEJ0 / dual specificity phosphatase 18ENSG0000016706514
DUSP22 / Q9NRW4 / dual specificity phosphatase 22ENSG0000011267913
DUSP13 / Q6B8I1 / Q9UII6 / dual specificity phosphatase 13ENSG0000007939313
DUSP14 / O95147 / dual specificity phosphatase 14ENSG0000027602313
DUPD1 / Q68J44 / dual specificity phosphatase and pro isomerase domain containing 1ENSG0000018871613
DUSP3 / P51452 / dual specificity phosphatase 3ENSG0000010886113
DUSP21 / Q9H596 / dual specificity phosphatase 21ENSG0000018903712


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR013087  Zinc finger C2H2-type
 IPR016278  Dual specificity protein phosphatase 12
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0033133 positive regulation of glucokinase activity IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IDA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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