ENSG00000198252


Homo sapiens

Features
Gene ID: ENSG00000198252
  
Biological name :STYX
  
Synonyms : Q8WUJ0 / serine/threonine/tyrosine interacting protein / STYX
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q22.1
Gene start: 52730180
Gene end: 52774998
  
Corresponding Affymetrix probe sets: 228853_at (Human Genome U133 Plus 2.0 Array)   235180_at (Human Genome U133 Plus 2.0 Array)   242408_at (Human Genome U133 Plus 2.0 Array)   244030_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000403214
Ensembl peptide - ENSP00000346599
NCBI entrez gene - 6815     See in Manteia.
OMIM - 615814
RefSeq - XM_011537109
RefSeq - NM_001130701
RefSeq - NM_145251
RefSeq - XM_006720242
RefSeq - XM_011537108
RefSeq Peptide - NP_001124173
RefSeq Peptide - NP_660294
swissprot - Q8WUJ0
swissprot - A0A024R641
Ensembl - ENSG00000198252
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 styxENSDARG00000057699Danio rerio
 Q60969ENSMUSG00000071748Mus musculus
 StyxENSMUSG00000053205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP27 / Q5VZP5 / dual specificity phosphatase 27, atypicalENSG0000019884227
DUSP14 / O95147 / dual specificity phosphatase 14ENSG0000027602327
DUSP19 / Q8WTR2 / dual specificity phosphatase 19ENSG0000016299926
DUSP22 / Q9NRW4 / dual specificity phosphatase 22ENSG0000011267925
DUSP12 / Q9UNI6 / dual specificity phosphatase 12ENSG0000008172125
DUSP15 / Q9H1R2 / dual specificity phosphatase 15ENSG0000014959924
DUPD1 / Q68J44 / dual specificity phosphatase and pro isomerase domain containing 1ENSG0000018871622
DUSP13 / Q6B8I1 / Q9UII6 / dual specificity phosphatase 13ENSG0000007939322
DUSP26 / Q9BV47 / dual specificity phosphatase 26ENSG0000013387821
DUSP3 / P51452 / dual specificity phosphatase 3ENSG0000010886121
DUSP21 / Q9H596 / dual specificity phosphatase 21ENSG0000018903721
DUSP18 / Q8NEJ0 / dual specificity phosphatase 18ENSG0000016706521
DUSP28 / Q4G0W2 / dual specificity phosphatase 28ENSG0000018854220


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007283 spermatogenesis IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0045204 MAPK export from nucleus IMP
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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