ENSG00000189037


Homo sapiens

Features
Gene ID: ENSG00000189037
  
Biological name :DUSP21
  
Synonyms : dual specificity phosphatase 21 / DUSP21 / Q9H596
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p11.3
Gene start: 44844004
Gene end: 44844888
  
Corresponding Affymetrix probe sets: 220515_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000343244
NCBI entrez gene - 63904     See in Manteia.
OMIM - 300678
RefSeq - NM_022076
RefSeq Peptide - NP_071359
swissprot - Q9H596
Ensembl - ENSG00000189037
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:153044ENSDARG00000067564Danio rerio
 ENSGALG00000007765Gallus gallus
 Dusp21ENSMUSG00000025043Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP18 / Q8NEJ0 / dual specificity phosphatase 18ENSG0000016706569
DUSP14 / O95147 / dual specificity phosphatase 14ENSG0000027602345
DUSP13 / Q6B8I1 / Q9UII6 / dual specificity phosphatase 13ENSG0000007939328
DUSP28 / Q4G0W2 / dual specificity phosphatase 28ENSG0000018854227
DUSP26 / Q9BV47 / dual specificity phosphatase 26ENSG0000013387827
DUSP27 / Q5VZP5 / dual specificity phosphatase 27, atypicalENSG0000019884226
DUSP19 / Q8WTR2 / dual specificity phosphatase 19ENSG0000016299925
DUSP15 / Q9H1R2 / dual specificity phosphatase 15ENSG0000014959925
DUPD1 / Q68J44 / dual specificity phosphatase and pro isomerase domain containing 1ENSG0000018871624
STYX / Q8WUJ0 / serine/threonine/tyrosine interacting proteinENSG0000019825224
DUSP3 / P51452 / dual specificity phosphatase 3ENSG0000010886123
DUSP22 / Q9NRW4 / dual specificity phosphatase 22ENSG0000011267923
DUSP12 / Q9UNI6 / dual specificity phosphatase 12ENSG0000008172121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020417  Atypical dual specificity phosphatase
 IPR020420  Atypical dual specificity phosphatase, subfamily B
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031314 extrinsic component of mitochondrial inner membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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