ENSG00000149599


Homo sapiens

Features
Gene ID: ENSG00000149599
  
Biological name :DUSP15
  
Synonyms : dual specificity phosphatase 15 / DUSP15 / Q9H1R2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q11.21
Gene start: 31847637
Gene end: 31870747
  
Corresponding Affymetrix probe sets: 230402_at (Human Genome U133 Plus 2.0 Array)   234829_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419818
Ensembl peptide - ENSP00000390355
Ensembl peptide - ENSP00000397486
Ensembl peptide - ENSP00000278979
Ensembl peptide - ENSP00000341658
Ensembl peptide - ENSP00000365133
Ensembl peptide - ENSP00000381157
Ensembl peptide - ENSP00000381158
NCBI entrez gene - 128853     See in Manteia.
OMIM - 616776
RefSeq - XM_017027662
RefSeq - NM_001012644
RefSeq - NM_001320478
RefSeq - NM_001320479
RefSeq - NM_080611
RefSeq - NM_177991
RefSeq - XM_017027654
RefSeq - XM_017027655
RefSeq - XM_017027656
RefSeq - XM_017027657
RefSeq - XM_017027658
RefSeq - XM_017027659
RefSeq - XM_017027660
RefSeq - XM_017027661
RefSeq Peptide - NP_001012662
RefSeq Peptide - NP_001307407
RefSeq Peptide - NP_001307408
RefSeq Peptide - NP_542178
RefSeq Peptide - NP_817130
swissprot - Q5QP64
swissprot - Q9H1R2
swissprot - H0Y5A2
Ensembl - ENSG00000149599
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DUSP15ENSGALG00000021017Gallus gallus
 Dusp15ENSMUSG00000042662Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP22 / Q9NRW4 / dual specificity phosphatase 22ENSG0000011267929
DUSP27 / Q5VZP5 / dual specificity phosphatase 27, atypicalENSG0000019884223
STYX / Q8WUJ0 / serine/threonine/tyrosine interacting proteinENSG0000019825218
DUSP28 / Q4G0W2 / dual specificity phosphatase 28ENSG0000018854217
DUSP12 / Q9UNI6 / dual specificity phosphatase 12ENSG0000008172117
DUSP19 / Q8WTR2 / dual specificity phosphatase 19ENSG0000016299916
DUSP18 / Q8NEJ0 / dual specificity phosphatase 18ENSG0000016706516
DUSP26 / Q9BV47 / dual specificity phosphatase 26ENSG0000013387816
DUSP21 / Q9H596 / dual specificity phosphatase 21ENSG0000018903716
DUSP14 / O95147 / dual specificity phosphatase 14ENSG0000027602316
DUSP3 / P51452 / dual specificity phosphatase 3ENSG0000010886115
DUSP13 / Q6B8I1 / Q9UII6 / dual specificity phosphatase 13ENSG0000007939314
DUPD1 / Q68J44 / dual specificity phosphatase and pro isomerase domain containing 1ENSG0000018871614


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR008984  SMAD/FHA domain superfamily
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR017855  SMAD-like domain superfamily
 IPR020417  Atypical dual specificity phosphatase
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IBA
 biological_processGO:0016311 dephosphorylation IDA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0046330 positive regulation of JNK cascade IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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