ENSG00000133878


Homo sapiens

Features
Gene ID: ENSG00000133878
  
Biological name :DUSP26
  
Synonyms : dual specificity phosphatase 26 / DUSP26 / Q9BV47
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p12
Gene start: 33591332
Gene end: 33600106
  
Corresponding Affymetrix probe sets: 219144_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430922
Ensembl peptide - ENSP00000256261
Ensembl peptide - ENSP00000429176
NCBI entrez gene - 78986     See in Manteia.
RefSeq - NM_001305116
RefSeq - NM_001305115
RefSeq - NM_024025
RefSeq Peptide - NP_001292044
RefSeq Peptide - NP_001292045
RefSeq Peptide - NP_076930
swissprot - Q9BV47
swissprot - E5RHD0
Ensembl - ENSG00000133878
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DUSP26ENSDARG00000103752Danio rerio
 DUSP26ENSGALG00000001633Gallus gallus
 Dusp26ENSMUSG00000039661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUPD1 / Q68J44 / dual specificity phosphatase and pro isomerase domain containing 1ENSG0000018871645
DUSP13 / Q6B8I1 / Q9UII6 / dual specificity phosphatase 13ENSG0000007939345
DUSP27 / Q5VZP5 / dual specificity phosphatase 27, atypicalENSG0000019884237
DUSP3 / P51452 / dual specificity phosphatase 3ENSG0000010886134
DUSP14 / O95147 / dual specificity phosphatase 14ENSG0000027602330
DUSP18 / Q8NEJ0 / dual specificity phosphatase 18ENSG0000016706527
DUSP21 / Q9H596 / dual specificity phosphatase 21ENSG0000018903724
DUSP19 / Q8WTR2 / dual specificity phosphatase 19ENSG0000016299924
DUSP28 / Q4G0W2 / dual specificity phosphatase 28ENSG0000018854223
DUSP15 / Q9H1R2 / dual specificity phosphatase 15ENSG0000014959923
DUSP22 / Q9NRW4 / dual specificity phosphatase 22ENSG0000011267923
DUSP12 / Q9UNI6 / dual specificity phosphatase 12ENSG0000008172122
STYX / Q8WUJ0 / serine/threonine/tyrosine interacting proteinENSG0000019825222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020405  Atypical dual specificity phosphatase, subfamily A
 IPR020417  Atypical dual specificity phosphatase
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IMP
 biological_processGO:0045785 positive regulation of cell adhesion IMP
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:1902310 positive regulation of peptidyl-serine dephosphorylation IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IPI
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0004647 phosphoserine phosphatase activity IMP
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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