ENSG00000188716


Homo sapiens

Features
Gene ID: ENSG00000188716
  
Biological name :DUPD1
  
Synonyms : dual specificity phosphatase and pro isomerase domain containing 1 / DUPD1 / Q68J44
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q22.2
Gene start: 75037836
Gene end: 75058514
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000340609
NCBI entrez gene - 338599     See in Manteia.
RefSeq - NM_001003892
RefSeq - XM_011539747
RefSeq Peptide - NP_001003892
swissprot - Q68J44
Ensembl - ENSG00000188716
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BX005321.1ENSDARG00000112213Danio rerio
 CU928063.1ENSDARG00000113659Danio rerio
 si:ch211-121a2.2ENSDARG00000039682Danio rerio
 si:dkey-194e6.2ENSDARG00000095001Danio rerio
 si:dkeyp-27c8.1ENSDARG00000092956Danio rerio
 si:dkeyp-27c8.1ENSDARG00000067808Danio rerio
 DUPD1ENSGALG00000005019Gallus gallus
 Dupd1ENSMUSG00000063821Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP26 / Q9BV47 / dual specificity phosphatase 26ENSG0000013387844
DUSP13 / Q6B8I1 / Q9UII6 / dual specificity phosphatase 13ENSG0000007939343
DUSP27 / Q5VZP5 / dual specificity phosphatase 27, atypicalENSG0000019884241
DUSP3 / P51452 / dual specificity phosphatase 3ENSG0000010886134
DUSP22 / Q9NRW4 / dual specificity phosphatase 22ENSG0000011267925
DUSP14 / O95147 / dual specificity phosphatase 14ENSG0000027602324
STYX / Q8WUJ0 / serine/threonine/tyrosine interacting proteinENSG0000019825223
DUSP18 / Q8NEJ0 / dual specificity phosphatase 18ENSG0000016706523
DUSP28 / Q4G0W2 / dual specificity phosphatase 28ENSG0000018854223
DUSP19 / Q8WTR2 / dual specificity phosphatase 19ENSG0000016299922
DUSP21 / Q9H596 / dual specificity phosphatase 21ENSG0000018903721
DUSP12 / Q9UNI6 / dual specificity phosphatase 12ENSG0000008172120
DUSP15 / Q9H1R2 / dual specificity phosphatase 15ENSG0000014959919


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020405  Atypical dual specificity phosphatase, subfamily A
 IPR020417  Atypical dual specificity phosphatase
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IDA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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