ENSG00000167065


Homo sapiens

Features
Gene ID: ENSG00000167065
  
Biological name :DUSP18
  
Synonyms : dual specificity phosphatase 18 / DUSP18 / Q8NEJ0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.2
Gene start: 30652051
Gene end: 30667890
  
Corresponding Affymetrix probe sets: 1553701_a_at (Human Genome U133 Plus 2.0 Array)   227098_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387680
Ensembl peptide - ENSP00000386063
Ensembl peptide - ENSP00000403378
Ensembl peptide - ENSP00000414825
Ensembl peptide - ENSP00000333917
Ensembl peptide - ENSP00000340795
Ensembl peptide - ENSP00000366291
Ensembl peptide - ENSP00000384946
Ensembl peptide - ENSP00000385463
NCBI entrez gene - 150290     See in Manteia.
OMIM - 611446
RefSeq - XM_017028628
RefSeq - NM_001304794
RefSeq - NM_001304795
RefSeq - NM_001304796
RefSeq - NM_152511
RefSeq - XM_005261368
RefSeq - XM_006724148
RefSeq - XM_011529920
RefSeq - XM_011529921
RefSeq - XM_017028627
RefSeq Peptide - NP_001291723
RefSeq Peptide - NP_001291725
RefSeq Peptide - NP_689724
RefSeq Peptide - NP_001291724
swissprot - H7C401
swissprot - Q8NEJ0
swissprot - A0A024R1L2
swissprot - C9JEE9
swissprot - F2Z2P2
swissprot - F8VX42
Ensembl - ENSG00000167065
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:153044ENSDARG00000067564Danio rerio
 ENSGALG00000007765Gallus gallus
 Dusp18ENSMUSG00000047205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP21 / Q9H596 / dual specificity phosphatase 21ENSG0000018903770
DUSP14 / O95147 / dual specificity phosphatase 14ENSG0000027602348
DUSP26 / Q9BV47 / dual specificity phosphatase 26ENSG0000013387831
DUSP13 / Q6B8I1 / Q9UII6 / dual specificity phosphatase 13ENSG0000007939329
DUSP28 / Q4G0W2 / dual specificity phosphatase 28ENSG0000018854228
DUSP22 / Q9NRW4 / dual specificity phosphatase 22ENSG0000011267927
DUPD1 / Q68J44 / dual specificity phosphatase and pro isomerase domain containing 1ENSG0000018871627
DUSP27 / Q5VZP5 / dual specificity phosphatase 27, atypicalENSG0000019884226
DUSP12 / Q9UNI6 / dual specificity phosphatase 12ENSG0000008172126
DUSP19 / Q8WTR2 / dual specificity phosphatase 19ENSG0000016299925
STYX / Q8WUJ0 / serine/threonine/tyrosine interacting proteinENSG0000019825225
DUSP15 / Q9H1R2 / dual specificity phosphatase 15ENSG0000014959924
DUSP3 / P51452 / dual specificity phosphatase 3ENSG0000010886123


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020417  Atypical dual specificity phosphatase
 IPR020420  Atypical dual specificity phosphatase, subfamily B
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0035970 peptidyl-threonine dephosphorylation IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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