Manteia

ENSMUSG00000047205

Mus musculus

Features

Gene ID:	ENSMUSG00000047205

Biological name :	Dusp18

Synonyms :	Dual specificity protein phosphatase 18 / Dusp18 / Q8VE01

Possible biological names infered from orthology :	dual specificity phosphatase 18 / Q8NEJ0

Species:	Mus musculus

Chr. number:	11
Strand:	1
Band:	A1
Gene start:	3895240
Gene end:	3901296

Corresponding Affymetrix probe sets:	10373810 (MoGene1.0st) 1437866_at (Mouse Genome 430 2.0 Array) 1451270_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000057346 Ensembl peptide - ENSMUSP00000105624 NCBI entrez gene - 75219 See in Manteia. MGI - MGI:1922469 RefSeq - XM_006514873 RefSeq - NM_173745 RefSeq Peptide - NP_776106 swissprot - Q8VE01 Ensembl - ENSMUSG00000047205

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
zgc:153044	ENSDARG00000067564	Danio rerio
	ENSGALG00000007765	Gallus gallus
DUSP18	ENSG00000167065	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Dusp21 / Q9D9D8 / Dual specificity phosphatase 21 / Q9H596*	ENSMUSG00000025043	70
Dusp14 / Q9JLY7 / Dual specificity protein phosphatase 14 / O95147* / dual specificity phosphatase 14*	ENSMUSG00000018648	50
Dusp26 / Q9D700 / Mus musculus dual specificity phosphatase 26 (putative) (Dusp26), transcript variant 2, mRNA. / Q9BV47* / dual specificity phosphatase 26*	ENSMUSG00000039661	31
Q9QYJ7 / Dusp13 / Q6B8I0 / Dual specificity protein phosphatase 13 isoform A / Q9UII6* / Q6B8I1* / dual specificity phosphatase 13*	ENSMUSG00000021768	29
Dusp28 / Q8BTR5 / Dual specificity phosphatase 28 / Q4G0W2*	ENSMUSG00000047067	28
Dusp27 / Q148W8 / Inactive dual specificity phosphatase 27 / Q5VZP5* / dual specificity phosphatase 27, atypical*	ENSMUSG00000026564	28
Dupd1 / Q8BK84 / Dual specificity phosphatase DUPD1 / Q68J44* / dual specificity phosphatase and pro isomerase domain containing 1*	ENSMUSG00000063821	27
Q60969 / Gm14698 / predicted gene 14698 / STYX* / Q8WUJ0* / serine/threonine/tyrosine interacting protein*	ENSMUSG00000071748	26
Styx / Q60969 / serine/threonine/tyrosine interaction protein / Q8WUJ0* / serine/threonine/tyrosine interacting protein*	ENSMUSG00000053205	26
Dusp22 / Q99N11 / Dual specificity protein phosphatase 22 / Q9NRW4* / dual specificity phosphatase 22*	ENSMUSG00000069255	26
Dusp12 / Q9D0T2 / Mus musculus dual specificity phosphatase 12 (Dusp12), transcript variant 3, mRNA. / Q9UNI6* / dual specificity phosphatase 12*	ENSMUSG00000026659	23
Dusp19 / dual specificity phosphatase 19 / Q8WTR2*	ENSMUSG00000027001	23
Dusp15 / Q8R4V2 / Dual specificity protein phosphatase 15 / Q9H1R2* / dual specificity phosphatase 15*	ENSMUSG00000042662	22
Dusp3 / Q9D7X3 / Dual specificity protein phosphatase 3 / P51452* / dual specificity phosphatase 3*	ENSMUSG00000003518	21

Protein motifs (from Interpro)

Interpro ID	Name
IPR000340	Dual specificity phosphatase, catalytic domain
IPR000387	Tyrosine specific protein phosphatases domain
IPR016130	Protein-tyrosine phosphatase, active site
IPR020417	Atypical dual specificity phosphatase
IPR020420	Atypical dual specificity phosphatase, subfamily B
IPR020422	Dual specificity protein phosphatase domain
IPR024950	Dual specificity phosphatase
IPR029021	Protein-tyrosine phosphatase-like

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000188	inactivation of MAPK activity	IEA
biological_process	GO:0006470	protein dephosphorylation	IEA
biological_process	GO:0006612	protein targeting to membrane	ISS
biological_process	GO:0006626	protein targeting to mitochondrion	ISS
biological_process	GO:0016311	dephosphorylation	ISS
biological_process	GO:0033365	protein localization to organelle	ISS
biological_process	GO:0035335	peptidyl-tyrosine dephosphorylation	IEA
biological_process	GO:0035970	peptidyl-threonine dephosphorylation	IEA
biological_process	GO:0046677	response to antibiotic	ISS
cellular_component	GO:0005634	nucleus	ISO
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005739	mitochondrion	ISS
cellular_component	GO:0005743	mitochondrial inner membrane	ISS
cellular_component	GO:0005758	mitochondrial intermembrane space	ISS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031304	intrinsic component of mitochondrial inner membrane	ISS
cellular_component	GO:0031314	extrinsic component of mitochondrial inner membrane	ISS
molecular_function	GO:0004721	phosphoprotein phosphatase activity	IEA
molecular_function	GO:0004725	protein tyrosine phosphatase activity	ISO
molecular_function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	ISS
molecular_function	GO:0016787	hydrolase activity	IEA
molecular_function	GO:0016791	phosphatase activity	ISS
molecular_function	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr