ENSMUSG00000042662


Mus musculus

Features
Gene ID: ENSMUSG00000042662
  
Biological name :Dusp15
  
Synonyms : Dual specificity protein phosphatase 15 / Dusp15 / Q8R4V2
  
Possible biological names infered from orthology : dual specificity phosphatase 15 / Q9H1R2
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H1
Gene start: 152940997
Gene end: 152951698
  
Corresponding Affymetrix probe sets: 10488678 (MoGene1.0st)   1426189_at (Mouse Genome 430 2.0 Array)   1435126_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045815
Ensembl peptide - ENSMUSP00000105436
Ensembl peptide - ENSMUSP00000123090
NCBI entrez gene - 252864     See in Manteia.
MGI - MGI:1934928
RefSeq - XM_011239560
RefSeq - NM_001159376
RefSeq - NM_145744
RefSeq - XM_006499542
RefSeq - XM_011239559
RefSeq Peptide - NP_001152848
RefSeq Peptide - NP_665687
swissprot - Q8R4V2
swissprot - A0A0A0MQD6
Ensembl - ENSMUSG00000042662
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DUSP15ENSGALG00000021017Gallus gallus
 DUSP15ENSG00000149599Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dusp22 / Q99N11 / Dual specificity protein phosphatase 22 / Q9NRW4* / dual specificity phosphatase 22*ENSMUSG0000006925539
Q60969 / Gm14698 / predicted gene 14698 / STYX* / Q8WUJ0* / serine/threonine/tyrosine interacting protein*ENSMUSG0000007174823
Dusp27 / Q148W8 / Inactive dual specificity phosphatase 27 / Q5VZP5* / dual specificity phosphatase 27, atypical*ENSMUSG0000002656423
Styx / Q60969 / serine/threonine/tyrosine interaction protein / Q8WUJ0* / serine/threonine/tyrosine interacting protein*ENSMUSG0000005320523
Dusp12 / Q9D0T2 / Mus musculus dual specificity phosphatase 12 (Dusp12), transcript variant 3, mRNA. / Q9UNI6* / dual specificity phosphatase 12*ENSMUSG0000002665922
Dusp21 / Q9D9D8 / Dual specificity phosphatase 21 / Q9H596*ENSMUSG0000002504321
Dusp14 / Q9JLY7 / Dual specificity protein phosphatase 14 / O95147* / dual specificity phosphatase 14*ENSMUSG0000001864821
Dusp26 / Q9D700 / Mus musculus dual specificity phosphatase 26 (putative) (Dusp26), transcript variant 2, mRNA. / Q9BV47* / dual specificity phosphatase 26*ENSMUSG0000003966121
Dusp3 / Q9D7X3 / Dual specificity protein phosphatase 3 / P51452* / dual specificity phosphatase 3*ENSMUSG0000000351820
Dusp19 / dual specificity phosphatase 19 / Q8WTR2*ENSMUSG0000002700120
Q9QYJ7 / Dusp13 / Q6B8I0 / Dual specificity protein phosphatase 13 isoform A / Q9UII6* / Q6B8I1* / dual specificity phosphatase 13*ENSMUSG0000002176819
Dusp18 / Q8VE01 / Dual specificity protein phosphatase 18 / Q8NEJ0* / dual specificity phosphatase 18*ENSMUSG0000004720518
Dusp28 / Q8BTR5 / Dual specificity phosphatase 28 / Q4G0W2*ENSMUSG0000004706717
Dupd1 / Q8BK84 / Dual specificity phosphatase DUPD1 / Q68J44* / dual specificity phosphatase and pro isomerase domain containing 1*ENSMUSG0000006382116


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020417  Atypical dual specificity phosphatase
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IBA
 biological_processGO:0016311 dephosphorylation ISO
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0046330 positive regulation of JNK cascade IBA
 biological_processGO:0048713 regulation of oligodendrocyte differentiation IMP
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity ISO
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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