ENSMUSG00000027364


Mus musculus

Features
Gene ID: ENSMUSG00000027364
  
Biological name :Usp50
  
Synonyms : Q6P8X6 / ubiquitin specific peptidase 50 / Usp50
  
Possible biological names infered from orthology : Q70EL3
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 126709096
Gene end: 126783470
  
Corresponding Affymetrix probe sets: 10487267 (MoGene1.0st)   10487269 (MoGene1.0st)   10569200 (MoGene1.0st)   1428296_at (Mouse Genome 430 2.0 Array)   1430760_a_at (Mouse Genome 430 2.0 Array)   1453670_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028842
Ensembl peptide - ENSMUSP00000121578
Ensembl peptide - ENSMUSP00000116873
NCBI entrez gene - 75083     See in Manteia.
MGI - MGI:1922333
RefSeq - NM_029163
RefSeq Peptide - NP_083439
swissprot - D6RCG3
swissprot - B0QZZ0
swissprot - Q6P8X6
Ensembl - ENSMUSG00000027364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP50ENSG00000170236Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Usp8 / Q80U87 / ubiquitin specific peptidase 8 / P40818*ENSMUSG0000002736337
Usp2 / O88623 / ubiquitin specific peptidase 2 / O75604*ENSMUSG0000003201033
Usp33 / Q8R5K2 / ubiquitin specific peptidase 33 / Q8TEY7*ENSMUSG0000002543732
Usp20 / Q8C6M1 / ubiquitin specific peptidase 20 / Q9Y2K6*ENSMUSG0000002685431
Usp21 / ubiquitin specific peptidase 21 / Q9UK80*ENSMUSG0000005348329
Usp45 / Q8K387 / ubiquitin specific petidase 45 / Q70EL2* / ubiquitin specific peptidase 45*ENSMUSG0000004045527
Usp16 / Q99LG0 / ubiquitin specific peptidase 16 / Q9Y5T5*ENSMUSG0000002561627


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001319 irregularly shaped pupil "shape defects in the aperture of the iris through which light rays enter the eye, usually circular " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Tmem79tm1.1(KOMP)Wtsi/Tmem79tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem79tm1.1(KOMP)Wtsi/J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Usp3tm1b(EUCOMM)Wtsi/Usp3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Usp3tm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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