ENSMUSG00000040455


Mus musculus

Features
Gene ID: ENSMUSG00000040455
  
Biological name :Usp45
  
Synonyms : Q8K387 / ubiquitin specific petidase 45 / Usp45
  
Possible biological names infered from orthology : Q70EL2 / ubiquitin specific peptidase 45
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A3
Gene start: 21767156
Gene end: 21837872
  
Corresponding Affymetrix probe sets: 10503551 (MoGene1.0st)   1427990_at (Mouse Genome 430 2.0 Array)   1427991_s_at (Mouse Genome 430 2.0 Array)   1430708_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000067109
Ensembl peptide - ENSMUSP00000127194
Ensembl peptide - ENSMUSP00000048324
Ensembl peptide - ENSMUSP00000128859
Ensembl peptide - ENSMUSP00000103867
Ensembl peptide - ENSMUSP00000125982
NCBI entrez gene - 77593     See in Manteia.
MGI - MGI:101850
RefSeq - XM_006538362
RefSeq - XM_006538361
RefSeq - XM_006538365
RefSeq - NM_001290425
RefSeq - NM_152825
RefSeq - XM_011250132
RefSeq - XM_006538364
RefSeq Peptide - NP_690038
RefSeq Peptide - NP_001277354
swissprot - Q8K387
swissprot - F7BAC1
swissprot - E9Q4D8
swissprot - F7CLE5
Ensembl - ENSMUSG00000040455
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp45ENSDARG00000075013Danio rerio
 ENSGALG00000031814Gallus gallus
 USP45ENSGALG00000015478Gallus gallus
 USP45ENSG00000123552Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Usp16 / Q99LG0 / ubiquitin specific peptidase 16 / Q9Y5T5*ENSMUSG0000002561637
Usp33 / Q8R5K2 / ubiquitin specific peptidase 33 / Q8TEY7*ENSMUSG0000002543718
Usp20 / Q8C6M1 / ubiquitin specific peptidase 20 / Q9Y2K6*ENSMUSG0000002685417
Usp2 / O88623 / ubiquitin specific peptidase 2 / O75604*ENSMUSG0000003201016
Usp8 / Q80U87 / ubiquitin specific peptidase 8 / P40818*ENSMUSG0000002736316
Usp21 / ubiquitin specific peptidase 21 / Q9UK80*ENSMUSG0000005348314
Usp50 / Q6P8X6 / ubiquitin specific peptidase 50 / Q70EL3*ENSMUSG0000002736413


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair ISO
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003549 Ercc1 / P07903 / DNA excision repair protein ERCC-1 / P07992* / ERCC excision repair 1, endonuclease non-catalytic subunit*  / reaction






 

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