ENSG00000123552


Homo sapiens

Features
Gene ID: ENSG00000123552
  
Biological name :USP45
  
Synonyms : Q70EL2 / ubiquitin specific peptidase 45 / USP45
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q16.2
Gene start: 99432379
Gene end: 99521728
  
Corresponding Affymetrix probe sets: 224441_s_at (Human Genome U133 Plus 2.0 Array)   238057_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423374
Ensembl peptide - ENSP00000423993
Ensembl peptide - ENSP00000426861
Ensembl peptide - ENSP00000425876
Ensembl peptide - ENSP00000424372
Ensembl peptide - ENSP00000330540
Ensembl peptide - ENSP00000333376
Ensembl peptide - ENSP00000358236
Ensembl peptide - ENSP00000421248
Ensembl peptide - ENSP00000421706
Ensembl peptide - ENSP00000422460
NCBI entrez gene - 85015     See in Manteia.
RefSeq - XM_017011386
RefSeq - NM_001080481
RefSeq - NM_001346022
RefSeq - NM_001346023
RefSeq - NM_032929
RefSeq - XM_005267169
RefSeq - XM_005267170
RefSeq - XM_005267172
RefSeq - XM_005267175
RefSeq - XM_011536200
RefSeq - XM_017011382
RefSeq - XM_017011383
RefSeq - XM_017011384
RefSeq - XM_017011385
RefSeq Peptide - NP_001332951
RefSeq Peptide - NP_001332952
RefSeq Peptide - NP_001332962
RefSeq Peptide - NP_116318
RefSeq Peptide - NP_001073950
RefSeq Peptide - NP_001332950
swissprot - H0Y8Q0
swissprot - H0Y986
swissprot - H0YA21
swissprot - Q70EL2
swissprot - D6RBV3
swissprot - E2QRF0
swissprot - D6RE98
swissprot - D6RC01
swissprot - H0Y8J5
Ensembl - ENSG00000123552
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp45ENSDARG00000075013Danio rerio
 ENSGALG00000031814Gallus gallus
 USP45ENSGALG00000015478Gallus gallus
 Usp45ENSMUSG00000040455Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP16 / Q9Y5T5 / ubiquitin specific peptidase 16ENSG0000015625638
USP20 / Q9Y2K6 / ubiquitin specific peptidase 20ENSG0000013687818
USP8 / P40818 / ubiquitin specific peptidase 8ENSG0000013859217
USP33 / Q8TEY7 / ubiquitin specific peptidase 33ENSG0000007725417
USP2 / O75604 / ubiquitin specific peptidase 2ENSG0000003667215
USP21 / Q9UK80 / ubiquitin specific peptidase 21ENSG0000014325814
USP50 / Q70EL3 / ubiquitin specific peptidase 50ENSG0000017023611


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0070911 global genome nucleotide-excision repair TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000012061 ERCC1 / P07992 / ERCC excision repair 1, endonuclease non-catalytic subunit  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr