ENSDARG00000075013


Danio rerio

Features
Gene ID: ENSDARG00000075013
  
Biological name :usp45
  
Synonyms : ubiquitin specific peptidase 45 / usp45
  
Possible biological names infered from orthology : Q70EL2 / Q8K387 / ubiquitin specific petidase 45
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 32676517
Gene end: 32727199
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000118184
NCBI entrez gene - 564004     See in Manteia.
swissprot - E9QG68
ZFIN ID - ZDB-GENE-100211-2
Ensembl - ENSDARG00000075013
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000031814Gallus gallus
 USP45ENSGALG00000015478Gallus gallus
 USP45ENSG00000123552Homo sapiens
 Usp45ENSMUSG00000040455Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
usp16 / A8HAL1 / ubiquitin specific peptidase 16 / Q99LG0* / Q9Y5T5*ENSDARG0000006063333
usp20 / A5PN09 / ubiquitin specific peptidase 20 / Q9Y2K6*ENSDARG0000002750118
usp33 / A5PMR2 / ubiquitin specific peptidase 33 / Q8R5K2* / Q8TEY7*ENSDARG0000001616317
usp8 / ubiquitin specific peptidase 8 / P40818* / Q80U87*ENSDARG0000006371916
usp2a / ubiquitin specific peptidase 2a / USP2* / O75604* / O88623* / ubiquitin specific peptidase 2*ENSDARG0000002010715
usp2b / ubiquitin specific peptidase 2b / USP2* / O75604* / O88623* / ubiquitin specific peptidase 2*ENSDARG0000007412015
usp21 / ubiquitin specific peptidase 21 / Q9UK80*ENSDARG0000009428014


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000031680 ercc1 / excision repair cross-complementation group 1 / P07992* / P07903* / DNA excision repair protein ERCC-1 * / ERCC excision repair 1, endonuclease non-catalytic subunit*  / reaction






 

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