ENSDARG00000027501


Danio rerio

Features
Gene ID: ENSDARG00000027501
  
Biological name :usp20
  
Synonyms : A5PN09 / ubiquitin specific peptidase 20 / usp20
  
Possible biological names infered from orthology : Q8C6M1 / Q9Y2K6
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 33301005
Gene end: 33330923
  
Corresponding Affymetrix probe sets: Dr.15440.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000014964
NCBI entrez gene - 393962     See in Manteia.
RefSeq - XM_009301457
RefSeq - XM_009301458
swissprot - F1QTS8
swissprot - A5PN09
ZFIN ID - ZDB-GENE-040426-1219
Ensembl - ENSDARG00000027501
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP20ENSGALG00000041104Gallus gallus
 USP20ENSG00000136878Homo sapiens
 Usp20ENSMUSG00000026854Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
usp33 / A5PMR2 / ubiquitin specific peptidase 33 / Q8R5K2* / Q8TEY7*ENSDARG0000001616360
usp45 / ubiquitin specific peptidase 45 / Q70EL2* / Q8K387* / ubiquitin specific petidase 45*ENSDARG0000007501316
usp16 / A8HAL1 / ubiquitin specific peptidase 16 / Q99LG0* / Q9Y5T5*ENSDARG0000006063315
usp8 / ubiquitin specific peptidase 8 / P40818* / Q80U87*ENSDARG0000006371915
usp2a / ubiquitin specific peptidase 2a / USP2* / O75604* / O88623* / ubiquitin specific peptidase 2*ENSDARG0000002010714
usp21 / ubiquitin specific peptidase 21 / Q9UK80*ENSDARG0000009428013
usp2b / ubiquitin specific peptidase 2b / USP2* / O75604* / O88623* / ubiquitin specific peptidase 2*ENSDARG0000007412013


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR006615  Peptidase C19, ubiquitin-specific peptidase, DUSP domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway ISS
 biological_processGO:0016579 protein deubiquitination ISS
 biological_processGO:0021551 central nervous system morphogenesis IMP
 biological_processGO:0070536 protein K63-linked deubiquitination ISS
 biological_processGO:0071108 protein K48-linked deubiquitination ISS
 biological_processGO:1904888 cranial skeletal system development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity ISS
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000155 somite somite fused with somite , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region curled , abnormal
post-vent region necrotic , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage morphology , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased size , abnormal
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 ZFA:0001405 ethmoid cartilage ethmoid cartilage shape , abnormal
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 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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