ENSG00000136878


Homo sapiens

Features
Gene ID: ENSG00000136878
  
Biological name :USP20
  
Synonyms : Q9Y2K6 / ubiquitin specific peptidase 20 / USP20
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 129834698
Gene end: 129881838
  
Corresponding Affymetrix probe sets: 203965_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000313811
Ensembl peptide - ENSP00000351122
Ensembl peptide - ENSP00000361506
NCBI entrez gene - 10868     See in Manteia.
OMIM - 615143
RefSeq - XM_017014221
RefSeq - NM_001008563
RefSeq - NM_001110303
RefSeq - NM_006676
RefSeq - XM_005251665
RefSeq - XM_005251666
RefSeq - XM_011518161
RefSeq - XM_011518162
RefSeq Peptide - NP_001103773
RefSeq Peptide - NP_006667
RefSeq Peptide - NP_001008563
swissprot - Q9Y2K6
Ensembl - ENSG00000136878
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp20ENSDARG00000027501Danio rerio
 USP20ENSGALG00000041104Gallus gallus
 Usp20ENSMUSG00000026854Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP33 / Q8TEY7 / ubiquitin specific peptidase 33ENSG0000007725460
USP8 / P40818 / ubiquitin specific peptidase 8ENSG0000013859216
USP16 / Q9Y5T5 / ubiquitin specific peptidase 16ENSG0000015625616
USP45 / Q70EL2 / ubiquitin specific peptidase 45ENSG0000012355216
USP2 / O75604 / ubiquitin specific peptidase 2ENSG0000003667215
USP21 / Q9UK80 / ubiquitin specific peptidase 21ENSG0000014325814
USP50 / Q70EL3 / ubiquitin specific peptidase 50ENSG0000017023610


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR006615  Peptidase C19, ubiquitin-specific peptidase, DUSP domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain
 IPR035927  DUSP-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IMP
 biological_processGO:0016579 protein deubiquitination IDA
 biological_processGO:0070536 protein K63-linked deubiquitination IDA
 biological_processGO:0071108 protein K48-linked deubiquitination IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IPI
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IMP
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000169252 ADRB2 / P07550 / adrenoceptor beta 2  / complex






 

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