ENSG00000156256


Homo sapiens

Features
Gene ID: ENSG00000156256
  
Biological name :USP16
  
Synonyms : Q9Y5T5 / ubiquitin specific peptidase 16 / USP16
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q21.3
Gene start: 29024629
Gene end: 29054488
  
Corresponding Affymetrix probe sets: 218386_x_at (Human Genome U133 Plus 2.0 Array)   222616_s_at (Human Genome U133 Plus 2.0 Array)   228822_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000334808
Ensembl peptide - ENSP00000382855
Ensembl peptide - ENSP00000382857
Ensembl peptide - ENSP00000382858
NCBI entrez gene - 10600     See in Manteia.
OMIM - 604735
RefSeq - XM_017028261
RefSeq - NM_001001992
RefSeq - NM_001032410
RefSeq - NM_006447
RefSeq - XM_017028257
RefSeq - XM_017028258
RefSeq - XM_017028259
RefSeq - XM_017028260
RefSeq Peptide - NP_001001992
RefSeq Peptide - NP_001027582
RefSeq Peptide - NP_006438
swissprot - H9KVB6
swissprot - Q9Y5T5
Ensembl - ENSG00000156256
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp16ENSDARG00000060633Danio rerio
 USP16ENSGALG00000015813Gallus gallus
 Usp16ENSMUSG00000025616Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP45 / Q70EL2 / ubiquitin specific peptidase 45ENSG0000012355238
USP33 / Q8TEY7 / ubiquitin specific peptidase 33ENSG0000007725419
USP20 / Q9Y2K6 / ubiquitin specific peptidase 20ENSG0000013687818
USP8 / P40818 / ubiquitin specific peptidase 8ENSG0000013859217
USP2 / O75604 / ubiquitin specific peptidase 2ENSG0000003667216
USP21 / Q9UK80 / ubiquitin specific peptidase 21ENSG0000014325814
USP50 / Q70EL3 / ubiquitin specific peptidase 50ENSG0000017023610


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain
 IPR030849  Ubiquitin carboxyl-terminal hydrolase 16


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0016578 histone deubiquitination IDA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0035522 monoubiquitinated histone H2A deubiquitination IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045901 positive regulation of translational elongation IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051289 protein homotetramerization IPI
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0070537 histone H2A K63-linked deubiquitination IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IMP
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity TAS
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0043130 ubiquitin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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