ENSMUSG00000027403


Mus musculus

Features
Gene ID: ENSMUSG00000027403
  
Biological name :Tgm6
  
Synonyms : Tgm6 / transglutaminase 6
  
Possible biological names infered from orthology : O95932
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F1
Gene start: 130112416
Gene end: 130154232
  
Corresponding Affymetrix probe sets: 10476058 (MoGene1.0st)   1437702_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028888
NCBI entrez gene - 241636     See in Manteia.
MGI - MGI:3044321
RefSeq - NM_001289749
RefSeq - NM_177726
RefSeq - XM_017318203
RefSeq - NM_001289747
RefSeq - NM_001289748
RefSeq Peptide - NP_001276677
RefSeq Peptide - NP_001276678
RefSeq Peptide - NP_808394
RefSeq Peptide - NP_001276676
swissprot - Q8BM11
Ensembl - ENSMUSG00000027403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tgm5lENSDARG00000098837Danio rerio
 tgm8ENSDARG00000097651Danio rerio
 TGM6ENSGALG00000021232Gallus gallus
 TGM6ENSG00000166948Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tgm3 / Q08189 / Protein-glutamine gamma-glutamyltransferase E Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain Protein-glutamine gamma-glutamyltransferase E 27 kDa non-ca...ENSMUSG0000002740149
Tgm5 / Q9D7I9 / Protein-glutamine gamma-glutamyltransferase 5 / O43548* / transglutaminase 5*ENSMUSG0000005367546
Tgm2 / P21981 / Protein-glutamine gamma-glutamyltransferase 2 / P21980* / transglutaminase 2*ENSMUSG0000003782039
Tgm7 / protein-glutamine gamma-glutamyltransferase Z / Q96PF1* / transglutaminase 7*ENSMUSG0000007910338
Tgm1 / transglutaminase 1 / P22735*ENSMUSG0000002221837
F13a1 / Q8BH61 / Coagulation factor XIII A chain / P00488*ENSMUSG0000003910934
Tgm4 / transglutaminase 4 / P49221*ENSMUSG0000002578734
Epb42 / P49222 / Erythrocyte membrane protein band 4.2 / P16452*ENSMUSG0000002321630


Protein motifs (from Interpro)
Interpro ID Name
 IPR001102  Transglutaminase, N-terminal
 IPR002931  Transglutaminase-like
 IPR008958  Transglutaminase, C-terminal
 IPR013783  Immunoglobulin-like fold
 IPR013808  Transglutaminase, active site
 IPR014756  Immunoglobulin E-set
 IPR023608  Protein-glutamine gamma-glutamyltransferase, animal
 IPR036238  Transglutaminase, C-terminal domain superfamily
 IPR036985  Transglutaminase-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0018149 peptide cross-linking IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003810 protein-glutamine gamma-glutamyltransferase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0001289 persistence of hyaloid capillary system "failure of the degeneration of the transient vascular system of the eye during development" [J:49840]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0004648 decreased thoracic vertebrae number "reduced number of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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