ENSMUSG00000027651


Mus musculus

Features
Gene ID: ENSMUSG00000027651
  
Biological name :Rprd1b
  
Synonyms : Q9CSU0 / Regulation of nuclear pre-mRNA domain-containing protein 1B / Rprd1b
  
Possible biological names infered from orthology : Q9NQG5 / regulation of nuclear pre-mRNA domain containing 1B
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 158028497
Gene end: 158132297
  
Corresponding Affymetrix probe sets: 10478022 (MoGene1.0st)   1427887_at (Mouse Genome 430 2.0 Array)   1441005_at (Mouse Genome 430 2.0 Array)   1452581_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122419
Ensembl peptide - ENSMUSP00000117807
Ensembl peptide - ENSMUSP00000118434
Ensembl peptide - ENSMUSP00000029180
Ensembl peptide - ENSMUSP00000099412
Ensembl peptide - ENSMUSP00000105144
NCBI entrez gene - 70470     See in Manteia.
MGI - MGI:1917720
RefSeq - XM_011239773
RefSeq - NM_001291134
RefSeq - NM_001291135
RefSeq - NM_001291136
RefSeq - NM_027434
RefSeq - XM_006500162
RefSeq - XM_006500163
RefSeq Peptide - NP_001278063
RefSeq Peptide - NP_001278064
RefSeq Peptide - NP_001278065
RefSeq Peptide - NP_081710
swissprot - Q9CSU0
swissprot - A0A0R4J195
swissprot - F7DAY5
swissprot - F6YB25
Ensembl - ENSMUSG00000027651
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rprd1bENSDARG00000038113Danio rerio
 RPRD1BENSGALG00000006788Gallus gallus
 Q9NQG5ENSG00000101413Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8VDS4 / Rprd1a / Regulation of nuclear pre-mRNA domain-containing protein 1A / Q96P16* / regulation of nuclear pre-mRNA domain containing 1A*ENSMUSG0000004044665
Rprd2 / Q6NXI6 / regulation of nuclear pre-mRNA domain containing 2 / Q5VT52*ENSMUSG0000002810626


Protein motifs (from Interpro)
Interpro ID Name
 IPR006569  CID domain
 IPR006903  RNA polymerase II-binding domain
 IPR008942  ENTH/VHS
 IPR032337  Cell-cycle alteration and expression-elevated protein in tumour


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0010564 regulation of cell cycle process ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0070940 dephosphorylation of RNA polymerase II C-terminal domain ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016591 DNA-directed RNA polymerase II, holoenzyme ISO
 molecular_functionGO:0000993 RNA polymerase II core binding ISO
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005641 increased mean corpuscular hemoglobin concentration "greater than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000040446 Q8VDS4 / Rprd1a / Regulation of nuclear pre-mRNA domain-containing protein 1A / Q96P16* / regulation of nuclear pre-mRNA domain containing 1A*  / complex
 ENSMUSG00000027651 Q9CSU0 / Rprd1b / Regulation of nuclear pre-mRNA domain-containing protein 1B / Q9NQG5* / regulation of nuclear pre-mRNA domain containing 1B*  / complex
 ENSMUSG00000033773 Rpap2 / Q8VC34 / Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 / Q8IXW5* / RNA polymerase II associated protein 2*  / reaction / complex
 ENSMUSG00000028106 Rprd2 / Q6NXI6 / regulation of nuclear pre-mRNA domain containing 2 / Q5VT52*  / reaction / complex






 

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