ENSMUSG00000027868


Mus musculus

Features
Gene ID: ENSMUSG00000027868
  
Biological name :Tbx15
  
Synonyms : O70306 / T-box transcription factor TBX15 / Tbx15
  
Possible biological names infered from orthology : Q96SF7 / T-box 15
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.2
Gene start: 99240381
Gene end: 99354259
  
Corresponding Affymetrix probe sets: 10494672 (MoGene1.0st)   1418755_at (Mouse Genome 430 2.0 Array)   1422195_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142358
Ensembl peptide - ENSMUSP00000143417
Ensembl peptide - ENSMUSP00000029462
NCBI entrez gene - 21384     See in Manteia.
MGI - MGI:1277234
RefSeq - XM_006501279
RefSeq - XM_006501280
RefSeq - NM_009323
RefSeq Peptide - NP_033349
swissprot - O70306
swissprot - A0A0G2JG43
swissprot - A0A0G2JDG4
Ensembl - ENSMUSG00000027868
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbx15ENSDARG00000002582Danio rerio
 TBX15ENSGALG00000014776Gallus gallus
 TBX15ENSG00000092607Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tbx18 / T-box 18 / O95935*ENSMUSG0000003241957
Tbx22 / Q8K402 / T-box 22 / Q9Y458*ENSMUSG0000003124140
Tbx20 / Q9ES03 / T-box transcription factor TBX20 / Q9UMR3* / T-box 20*ENSMUSG0000003196529
Tbx1 / T-box 1 / O43435*ENSMUSG0000000909726
Tbx3 / P70324 / T-box 3 / O15119*ENSMUSG0000001860426
Tbx2 / Q60707 / T-box transcription factor TBX2 / Q13207* / T-box 2*ENSMUSG0000000009326
Tbx5 / P70326 / T-box 5 / Q99593*ENSMUSG0000001826324
Tbx4 / P70325 / T-box 4 / P57082*ENSMUSG0000000009424
Tbx10 / Q810F8 / T-box transcription factor TBX10 / O75333* / T-box 10*ENSMUSG0000003747723
Tbx6 / P70327 / T-box transcription factor TBX6 / O95947* / T-box 6*ENSMUSG0000003069921


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site
 IPR036960  T-box superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0048704 embryonic skeletal system morphogenesis IMP
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0070722 Tle3-Aes complex IDA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000023 abnormal ear distance/ position "anomaly in the space between or the placement of the outer ears " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0000024 lowered ear position "outer ears which are situated below the normal location " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

 MP:0000074 abnormal neurocranium morphology "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0000078 abnormal supraoccipital bone morphology "malformed upper part of the occipital bone" [J:61509]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0000079 abnormal basioccipital bone morphology "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0000088 short mandible "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15+
Genetic Background: involves: C3H * C57BL/6J

 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0000149 abnormal scapula morphology "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15+
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4lst-J/Alx4lst-J,Tbx15de-H/Tbx15+
Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6J

 MP:0000167 reduced chondrocyte numbers "fewer than normal numbers of nondividing cartilage cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61509]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0000372 irregular coat pigmentation "uneven coloration of the hair" [J:65030]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

Allelic Composition: Tbx15de/Tbx15de
Genetic Background: STOCK J

 MP:0000417 short hair "reduced average length of the hairs" [J:64948]
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Allelic Composition: ae/ae,Tbx15de-H/Tbx15de-H
Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fbxw7tm1Kei/Fbxw7tm1Kei,Rbpjtm1Hon/Rbpjtm1Hon,Tg(Cd4-cre)1Cwi/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

 MP:0000435 shortened head "reduced anterior-posterior length of the head" [J:42035]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

Allelic Composition: Tbx15de/Tbx15de
Genetic Background: STOCK J

 MP:0000449 broad nasal bridge "wider than normal upper part of the ridge of the nose" [J:53370]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

Allelic Composition: Tbx15de/Tbx15de
Genetic Background: STOCK J

 MP:0000552 abnormal radius morphology "malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Tbx15tm1Apr/Tbx15tm1Apr
Genetic Background: involves: C57BL/6

Allelic Composition: ae/ae,Tbx15de-H/Tbx15de-H
Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S

 MP:0001300 ocular hypertelorism "increased distance between the eyes " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0001382 abnormal nursing "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0001731 abnormal postnatal growth "anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx15de/Tbx15de
Genetic Background: STOCK J

 MP:0001921 reduced fertility "diminished ability to produce live offspring" [J:65030]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Adamts1tm1Mapr/Adamts1tm1Mapr
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002095 abnormal skin pigmentation "variation of skin color or complexion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: ae/ae,Tbx15de-H/Tbx15de-H
Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rasgrf1tm1Sva/Rasgrf1tm1Sva
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0002115 abnormal skeleton extremities morphology "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Rasgrf1tm1Sva/Rasgrf1tm1Sva
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0003109 short femur "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0003419 delayed endochondral bone ossification "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004338 small clavicle "reduced size of one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004339 absent clavicle "missing one or both of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0004342 scapular bone foramen "presence of a hole in either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15+
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Tbx15de-H/Tbx15de-H
Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6JEi

 MP:0004343 small scapula "reduced size of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15de/Tbx15de
Genetic Background: STOCK J

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15de-H
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4lst-J/Alx4lst-J,Tbx15de-H/Tbx15de-H
Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6J

 MP:0004345 abnormal acromion morphology "any structural anomaly of the lateral end of the spine of the scapula which projects as a broad flattened process and articulates with the clavicle, and forms the point of the shoulder" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15de/Tbx15de
Genetic Background: STOCK J

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15de-H
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0004347 abnormal scapular spine morphology "any structural anomaly of the trianguar ridge on the dorsal aspect of the scapula which separates the supra- from the infraspinatous fossa and where the trapezius and deltoid muscles are attached " [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4lst-J/Alx4lst-J,Tbx15de-H/Tbx15+
Genetic Background: involves: 129S7/SvEvBrd * C3H * C57BL/6J

 MP:0004351 short humerus "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004353 abnormal deltoid tuberosity morphology "any structural anomaly of a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004355 short radius "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004359 short ulna "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004447 small basioccipital bone "reduced size of the bone in the base of the cranium, frequently forming a part of the occipital in the adult, but usually distinct in the young" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004508 abnormal shoulder bone morphology "any structural anomaly of the bones of the shoulder by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0004596 abnormal mandibular angle morphology "any structural anomaly of the portion of the mandible where the body of the mandible (horizontal portion) and the rami (perpendicular portions) meet; these normally unite nearly at right angles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0004599 abnormal vertebral arch morphology "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0004607 abnormal cervical atlas morphology "any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0004608 abnormal cervical axis morphology "any structural anomaly of the second cervical vertebra (C2) which forms the pivot upon which the first cervical (atlas, C1) vertebra rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004634 short metacarpal bones "reduced length of the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004635 short metatarsal bones "reduced length of the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0004659 abnormal odontoid process "any structural anomaly of the large protuberance that projects upward from the cervical axis, around which the cervical atlas rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A02.835.232.834.151.383.668]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0004819 decreased skeletal muscle mass "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0005108 abnormal ulna morphology "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0005269 abnormal occipital bone morphology "anomalous structure of the bone at the lower, posterior part of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0005272 abnormal temporal bone morphology "anomalous structure of the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0005287 narrow eye opening "less than the normal distance from one eyelid to the other " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:71350]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

 MP:0005296 abnormal humerus morphology "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0005306 abnormal phalanx morphology "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

Allelic Composition: ae/ae,Tbx15de-H/Tbx15de-H
Genetic Background: involves: BTBR * C3H/HeJ * C57BL/6 * P * S

 MP:0005650 abnormal limb bud morphology "aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0008154 decreased diameter of humerus "reduced width of the cross-sectional distance that extends from one lateral edge of the humerus, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0008237 abnormal ventral coat pigmentation "irregular or unusual pigmentation of ventrum hair in relation to control animals" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

 MP:0008238 abnormal dorsoventral coat patterning "irregular or unusual pigmentation pattern of the dorsal-to-ventral axis compared to control animals" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

 MP:0008525 decreased skull height "decrease in the distance between the cranial base and the upper domelike portion of the skull" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0008526 decreased skull width "having a decreased side-to-side distance of the skull" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tbx15de-H/Tbx15de-H
Genetic Background: B6EiC3 a/A-Tbx15de-H/J

 MP:0010941 abnormal foramen magnum morphology "any structural anomaly of the large orifice in the occipital bone through which the spinal cord passes to the cranial cavity and becomes continuous with the medulla oblongata" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Tbx15de/Tbx15de
Genetic Background: STOCK J

 MP:0030189 broad snout "increased width of the anterior facial part of the face or muzzle containing the oral and nasal regions" [MGI:anna]
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Allelic Composition: Tbx15tm1Akis/Tbx15tm1Akis
Genetic Background: involves: 129P2/OlaHsd * NMRI

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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